Corelate TCR data to clusters/GEX/CITEseq data

Corelate TCR data to clusters/GEX/CITEseq data

1

Hello everyone,

I just added my TCR VDJ data as metadata to my Seurat object (as described in the tutorial here). So, I basically ended up with two different collumns of metadata where my barcodes are assigned to the clonotypes and the cdr3 sequences.
As a next step I would like to correlate my clonotypes to certain features of my gene expression or my Cite seq data. Or for example check the frequency of a certain clonotype within each of my umap clusters.

Does anyone have in mind any way or package that would help me with this approach?

Thanks a lot in advance


10x


vdj


tcr


seurat

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