Bioinformatics Scientist
ORAU – Bethesda, MD
Overview:
ORAU has a contingent job opportunity for a Bioinformatics Scientist in support of in support of the overall functions of the Research Technologies Branch (RTB), Integrated Data Sciences Section (IDSS), National Institutes for Health (NIH), located in Bethesda, MD. The positions are contingent on award of an upcoming contract with NIAID Professional, Scientific and Technical Support Services. Salary for positions will be determined based on education and experience. Relocation support is not available for this position.
ORAU has been providing scientific and technical talent staffing solutions and designing, managing, and evaluating jobs and internships for more than 70 years. ORAU assists in connecting the best and most diverse group of students, recent graduates, faculty and professionals with world-class fellowships, internships and job opportunities, whether in national laboratories, research institutions, federal government offices or private sector R&D departments.
Responsibilities:
Provide programming and troubleshooting support to the RTB in the dissemination of research data. Perform computation on research data analysis. Work with staff on scientific programming and experimental design. Provide statistical support/analysis on research data.
Address bioinformatics, scientific computing, and data analysis needs of users within the Division of Intramural Research (DIR) by lending expertise in the proper statistical design of biological experiments involving high-throughput technologies, data mining and knowledge discovery techniques, and data workflow applications development as well as performing microarray data analysis for research activities and providing statistical and scientific consultancy for microarray experimental design, data collection, and platform option. Provide bioinformatics support to include array probe design, gene content, and sequence analysis.
Perform a wide variety of complex procedures and techniques in support of RTB including Affymetrix fluidics and hybridization protocols; high-throughput TaqMan processing; microarray data analysis; high-throughput SNP processing; allelic discrimination assays; genotyping; robotic manipulations for fluidic and high throughput sample preparations; single and multichannel pipettor manipulations; DNA sequencing.
Create a scalable and flexible resource to provide NGS bioinformatics, structural biological and computational, machine learning data support to NIAID scientists and investigators. It is expected that the bioinformatics analysts will need strong skills in the following:
NGS analysis (whole-exome, whole-genome, RNA-seq, ChIP-Seq, etc.)
Statistical models,
Scripting, and biological interpretation
Estimate of NIAID Projects and number of investigators per year
Project Type
Number of Investigators/PIs
Number of samples per project
RNA-Seq
20
25-50
Whole Exome/genome sequencing
15
25-50
Methylation & RNA
5
25-50
ChIP-Seq Variants
10
20-30
Bacterial/Microbiome (Pac Bio)
5
10-15
Structural/Imaging analysis
10
N/A
Qualifications:
Minimum Bachelor’s degree in related field.
Four (4) years of experience in a related field.
Experience working in a laboratory setting is a plus.
Expertise with Microsoft Office (Word, Excel, etc.)..
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