Gene co-expression in single-cell RNA-seq

Gene co-expression in single-cell RNA-seq

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I am using single-cell RNA-seq data from the Allen Institute, and I want to look at gene co-expression in different cell populations. They provide raw UMI counts, so I’m wondering what normalization method to use (e.g., CPM, TPM, VST) to look at these correlations. Any rationale/justification is appreciated.


single-cell


scRNA-seq


RNA-seq


correlation


co-expression

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