Bioconductor – cageminer (development version)

DOI: 10.18129/B9.bioc.cageminer  

 

This is the development version of cageminer; to use it, please install the devel version of Bioconductor.

Candidate Gene Miner

Bioconductor version: Development (3.14)

This package aims to integrate GWAS-derived SNPs and coexpression networks to mine candidate genes associated with a particular phenotype. For that, users must define a set of guide genes, which are known genes involved in the studied phenotype. Additionally, the mined candidates can be given a score that favor candidates that are hubs and/or transcription factors. The scores can then be used to rank and select the top n most promising genes for downstream experiments.

Author: Fabrício Almeida-Silva [aut, cre] , Thiago Venancio [aut]

Maintainer: Fabrício Almeida-Silva <fabricio_almeidasilva at hotmail.com>

Citation (from within R,
enter citation("cageminer")):

Installation

To install this package, start R (version
“4.1”) and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

# The following initializes usage of Bioc devel
BiocManager::install(version='devel')

BiocManager::install("cageminer")

For older versions of R, please refer to the appropriate
Bioconductor release.

Documentation

To view documentation for the version of this package installed
in your system, start R and enter:

browseVignettes("cageminer")

 

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R Script

Mining high-confidence candidate genes with cageminer
PDF   Reference Manual
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Details

biocViews FunctionalGenomics, FunctionalPrediction, GeneExpression, GenomeWideAssociation, Network, NetworkEnrichment, SNP, Software, VariantAnnotation
Version 0.99.7
In Bioconductor since BioC 3.14 (R-4.1)
License GPL-3
Depends R (>= 4.1)
Imports ggplot2, ggbio, ggtext, GenomeInfoDb, GenomicRanges, IRanges, reshape2, methods, BioNERO
LinkingTo
Suggests testthat (>= 3.0.0), SummarizedExperiment, knitr, BiocStyle, rmarkdown
SystemRequirements
Enhances
URL github.com/almeidasilvaf/cageminer
BugReports support.bioconductor.org/t/cageminer
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Imports Me
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Build Report  

Package Archives

Follow
Installation
instructions to use this
package in your R session.

Read more here: Source link