This package is for version 3.12 of Bioconductor;
for the stable, up-to-date release version, see
Clomial.
Infers clonal composition of a tumor
Bioconductor version: 3.12
Clomial fits binomial distributions to counts obtained from Next Gen Sequencing data of multiple samples of the same tumor. The trained parameters can be interpreted to infer the clonal structure of the tumor.
Author: Habil Zare and Alex Hu
Maintainer: Habil Zare <zare at u.washington.edu>
Citation (from within R,
enter citation("Clomial")
):
Installation
To install this package, start R (version
“4.0”) and enter:
if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("Clomial")
For older versions of R, please refer to the appropriate
Bioconductor release.
Documentation
To view documentation for the version of this package installed
in your system, start R and enter:
browseVignettes("Clomial")
A likelihood maximization approach to infer the clonal structure of a cancer using multiple tumor samples | ||
Reference Manual | ||
Text | NEWS |
Details
biocViews | Bayesian, Clustering, DNASeq, ExomeSeq, GeneticVariability, Genetics, ImmunoOncology, MultipleComparison, Sequencing, Software, TargetedResequencing |
Version | 1.26.0 |
In Bioconductor since | BioC 2.14 (R-3.1) (7 years) |
License | GPL (>= 2) |
Depends | R (>= 2.10), matrixStats |
Imports | methods, permute |
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