Bioconductor – ramr

DOI: 10.18129/B9.bioc.ramr  

 

Detection of Rare Aberrantly Methylated Regions in Array and NGS Data

Bioconductor version: Release (3.13)

ramr is an R package for detection of low-frequency aberrant methylation events in large data sets obtained by methylation profiling using array or high-throughput bisulfite sequencing. In addition, package provides functions to visualize found aberrantly methylated regions (AMRs), to generate sets of all possible regions to be used as reference sets for enrichment analysis, and to generate biologically relevant test data sets for performance evaluation of AMR/DMR search algorithms.

Author: Oleksii Nikolaienko [aut, cre]

Maintainer: Oleksii Nikolaienko <oleksii.nikolaienko at gmail.com>

Citation (from within R,
enter citation("ramr")):

Installation

To install this package, start R (version
“4.1”) and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("ramr")

For older versions of R, please refer to the appropriate
Bioconductor release.

Documentation

To view documentation for the version of this package installed
in your system, start R and enter:

browseVignettes("ramr")

 

Details

biocViews DNAMethylation, DifferentialMethylation, Epigenetics, MethylSeq, MethylationArray, Software
Version 1.0.3
In Bioconductor since BioC 3.13 (R-4.1) (
License Artistic-2.0
Depends R (>= 4.1), GenomicRanges, parallel, doParallel, foreach, doRNG, methods
Imports IRanges, BiocGenerics, ggplot2, reshape2, EnvStats, ExtDist, matrixStats, S4Vectors
LinkingTo
Suggests RUnit, knitr, rmarkdown, gridExtra, annotatr, LOLA, org.Hs.eg.db, TxDb.Hsapiens.UCSC.hg19.knownGene
SystemRequirements
Enhances
URL github.com/BBCG/ramr
BugReports github.com/BBCG/ramr/issues
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Build Report  

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