Cell type deconvolution from Bulk RNA-seq data

Cell type deconvolution from Bulk RNA-seq data

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Hi everyone.

I have brain RNA-seq data and a number of significantly DEGs. I also have a list of marker genes for astrocytes, neurons, microglia, oligodendrocytes, endothelial cells. I’ve read in some papers that they use a one-sided fisher’s test to do the cell type deconvolution analysis to find out which cell types are more affected than others. Does anyone have any code they could share or advice on how to do this?

Thanks.


cell-type


RNA-seq


digital


cytometry

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