DOI: 10.18129/B9.bioc.RTN
This package is for version 3.12 of Bioconductor;
for the stable, up-to-date release version, see
RTN.
RTN: Reconstruction of Transcriptional regulatory Networks and analysis of regulons
Bioconductor version: 3.12
A transcriptional regulatory network (TRN) consists of a collection of transcription factors (TFs) and the regulated target genes. TFs are regulators that recognize specific DNA sequences and guide the expression of the genome, either activating or repressing the expression the target genes. The set of genes controlled by the same TF forms a regulon. This package provides classes and methods for the reconstruction of TRNs and analysis of regulons.
Author: Clarice Groeneveld [ctb], Gordon Robertson [ctb], Xin Wang [aut], Michael Fletcher [aut], Florian Markowetz [aut], Kerstin Meyer [aut], and Mauro Castro [aut]
Maintainer: Mauro Castro <mauro.a.castro at gmail.com>
Citation (from within R,
enter citation("RTN")):
Installation
To install this package, start R (version
“4.0”) and enter:
if (!requireNamespace("BiocManager", quietly = TRUE))
install.packages("BiocManager")
BiocManager::install("RTN")
For older versions of R, please refer to the appropriate
Bioconductor release.
Documentation
To view documentation for the version of this package installed
in your system, start R and enter:
browseVignettes("RTN")
| RTN: reconstruction of transcriptional regulatory networks and analysis of regulons.” | ||
| Reference Manual | ||
| Text | NEWS |
Details
| biocViews | GeneExpression, GeneRegulation, GeneSetEnrichment, GeneticVariability, GraphAndNetwork, Network, NetworkEnrichment, NetworkInference, Software, Transcription |
| Version | 2.14.1 |
| In Bioconductor since | BioC 2.13 (R-3.0) (7.5 years) |
| License | Artistic-2.0 |
| Depends | R (>= 3.6.3), methods |
| Imports | RedeR, minet, viper, mixtools, snow, stats, limma, data.table, IRanges, igraph, S4Vectors, SummarizedExperiment, car, pwr, pheatmap, grDevices, graphics, utils |
| LinkingTo | |
| Suggests | RUnit, BiocGenerics, BiocStyle, knitr, rmarkdown |
| SystemRequirements | |
| Enhances | |
| URL | dx.doi.org/10.1038/ncomms3464 |
| Depends On Me | Fletcher2013b, RTNduals, RTNsurvival |
| Imports Me | |
| Suggests Me | geneplast |
| Links To Me | |
| Build Report |
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