Low number of nCount_RNA in single-cell RNAseq clusters?

Low number of nCount_RNA in single-cell RNAseq clusters? 0 Hello, after standard Seurat workflow, I checked the metrics of each cluster in the object. Please see the attached picture. How may I explain, in some of clusters, such as cluster 9 which has low nCount_RNA and nFeature_RNA but with an…

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Whole Transcriptome Data Analysis Course, EMBL Advanced Training Centre, Heidelberg, Baden-Wurttemberg, Germany

Overview Whole Transcriptome Data Analysis Course is organized by European Molecular Biology Laboratory (EMBL) and will be held from May 21 – 26, 2023 at EMBL Advanced Training Centre, Heidelberg, Baden-Wurttemberg, Germany. Description:This course will teach biological researchers how to analyze biological data sets using open-source software. Most of the…

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Comparative chloroplast genome and phylogenetic analyses of Chinese Polyspora

Choo, L. M., Niissalo, M. A., Leong, P. K. F. & Khew, G. S. The complete plastome sequence of Gordonia penangensis Ridl. supports the transfer of Asian Gordonia into Polyspora (Theaceae). Phytotaxa 458, 159–166 (2020). Nguyet, H. N. L. et al. An updated checklist of Theaceae and a new species…

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Special Issue : Recent Advances in Chemical Biology to Study and Target ncRNAs

Dear Colleagues, In recent decades, ncRNAs have been shown to play a critical role in a myriad of cellular processes, impacting normal gene expression as well as disease progression, making them an attractive target for drug discovery. Moreover, their complex impacts on molecular biology still require revealing and studying. Recent…

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python – scikit-learn RandomizedSearchCV doesn’t utilise all available cores

I’m using RandomizedSearchCV to optimize and evaluate several ML models. I’m trying to run the optimization process using joblib Parallel(). But, when running my code on an HPC using 16 cores, only two of them are used. jobs = 16 x = Parallel(n_jobs=jobs, backend=’multiprocessing’, verbose=3)(delayed(fit)(m, X_train, y_train, n_iter= 3, cv…

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NM_005359.6(SMAD4):c.1630C>A (p.Pro544Thr) AND Hereditary cancer-predisposing syndrome – ClinVar

NM_005359.6(SMAD4):c.1630C>A (p.Pro544Thr) AND Hereditary cancer-predisposing syndrome Based on: 1 submission [Details] Record status: current Accession: RCV001012497.1 Allele description [Variation Report for NM_005359.6(SMAD4):c.1630C>A (p.Pro544Thr)] NM_005359.6(SMAD4):c.1630C>A (p.Pro544Thr) Gene: SMAD4:SMAD family member 4 [Gene – OMIM – HGNC] Variant type: single nucleotide variant Cytogenetic location: 18q21.2 Genomic location: Preferred name: NM_005359.6(SMAD4):c.1630C>A (p.Pro544Thr) HGVS:…

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FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A

. 2022 Sep 14;2022:3242482. doi: 10.1155/2022/3242482. eCollection 2022. Affiliations Expand Affiliation 1 College of Clinical Medicine, Guizhou Medical University, Guiyang, 550000 Guizhou, China. Item in Clipboard Xing Wang et al. Stem Cells Int. 2022. Show details Display options Display options Format AbstractPubMedPMID . 2022 Sep 14;2022:3242482. doi: 10.1155/2022/3242482. eCollection 2022. Affiliation…

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Modelling urea cycle disorders using iPSCs

Gebhardt, R. & Matz-Soja, M. Liver zonation: Novel aspects of its regulation and its impact on homeostasis. World J. Gastroenterol. 20, 8491–8504 (2014). PubMed  PubMed Central  Article  Google Scholar  Summar, M. L. et al. The incidence of urea cycle disorders. Mol. Genet Metab. 110, 179–180 (2013). CAS  PubMed  PubMed Central …

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Dextromethorphan-Bupropion in Depression

A new—cough, cough—combination treatment for depression. Researchers performed an RCT of dextromethorphan-bupropion in major depressive disorder. RESEARCH UPDATE Partial or inadequate response to antidepressants—whose mechanisms primarily involve monoamine pathways—are common.1,2 Multiple lines of evidence suggest that the glutamatergic system is also involved in the pathophysiology of depression. Dextromethorpahn is a…

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Get stdout/stderr from a slurm job at runtime

I have a batch file to send a job with sbatch.The contents of the batch file is # Setting the proper SBATCH variables … #SBATCH –error=”test_slurm-%j.err” #SBATCH –output=”test_slurm-%j.out” … WORKDIR=. echo “Run 1” ${WORKDIR}/test_slurm echo “Run 2” ${WORKDIR}/test_slurm File test_slurm-%j.out is sometimes appended with output only after each of the…

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Solved Fredrick Wilson and his colleagues studied members of

Transcribed image text: Fredrick Wilson and his colleagues studied members of a large family who had low levels of magnesium in their blood (see the pedigree). They argued that this disorder of magnesium (and associated high blood pressure and high cholesterol) is caused by a mutation in mtDNA (F. H….

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Gut Microbiome Could Play Role in MS

By By Cara Murez HealthDay Reporter, HealthDay Reporter (HealthDay) MONDAY, Sept. 26, 2022 (HealthDay News) — Scientists have been looking to the microbiome, and its numerous gut bacteria, as an area of research with plenty of potential for finding connections to various diseases. Now, scientists have found evidence of significant…

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Grabled LOG-file after running 2e6 steps – LAMMPS General Discussion

Hello guys! Recently I ran an Equilibrium of my model(see attachment), and try to get density, energy and steps out of it. After running 2e6 steps, 2e5 lines of data should be output, but there are a lot of garbled characters in the obtained log file (see attachment) and only…

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Gromacs: gmx::anonymous_namespace{electricfield.cpp}::ElectricField Class Reference

Describe time dependent electric field. Class that implements a force to be evaluated in mdrun. The electric field can be pulsed and oscillating, simply oscillating, or static, in each of X,Y,Z directions. Initializes a transform from mdp values to sectioned options. The transform is specified from a flat KeyValueTreeObject that…

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Same results in Limma Toptable as in DESEQ2 results

Same results in Limma Toptable as in DESEQ2 results 1 Dear all, I am trying to generate exactly the same results in Limma for my result table as I did in DESEQ2 (Differential Expression Analysis). With the toptable function I am not getting lfcSE and basemean. Can anyone help me…

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Confrontation of AlphaFold models with experimental structures enlightens conformational dynamics supporting CYP102A1 functions

Prediction of alternate structures of CYP102A1 The competitive modelling approach was designed considering that the CYP102A1 FMNd must form alternate electron transfer complexes with the FADd and the P450d to support catalytic cycles, but that a direct electron transfer from FADd to P450d is not possible. In the dimeric structure…

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Project Scientist – Knott Lab – Bioinformatics & Functional Genomics

Are you passionate about applying genomics, computer science, and probability theory to study cancer progression? The Knott laboratory at Cedars-Sinai Medical Center is searching for a Project Scientist with a strong background in tumor biology and the immune microenvironment to lead single cell-based omics studies of immunotherapy clinical trials being…

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Latest Bioinformatics Jobs – Internshala

In India, about 65-70% women who take a career break fail to return to work, and a large number of women who are well educated & have potential to become a valuable part of the workforce do not even get a chance to begin their career. “Internships for Women” brings…

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How do I get separate ADT / CITE-seq fastq’s from single SRA / BAM files? (originally generated from cellranger)

How do I get separate ADT / CITE-seq fastq’s from single SRA / BAM files? (originally generated from cellranger) 0 Hello all. I am trying to pre-process some single cell RNA and ADT (Totalseq-C) data from an GEO SRA, but having some issues getting separate fastq’s for the “CITE-seq” (ADT)…

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GATK vs DeepVariant : bioinformatics

Hi everyone, I am currently working on a medium-sized WES cohort study and wanted to know what the bioinformatics community would regard a cutting-edge workflow. As the big labs usually utilize GATK I also started with that. The results for SNPs are ok, but manual inspection (IGV) still uncovers a…

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Protocol for single-nucleus ATAC sequencing and bioinformatic analysis in frozen human brain tissue.

Abstract Single-nucleus ATAC sequencing (snATAC-seq) employs a hyperactive Tn5 transposase to gain precise information about the cis-regulatory elements in specific cell types. However, the standard protocol of snATAC-seq is not optimized for all tissues, including the brain. Here, we present a modified protocol for single-nuclei isolation from postmortem frozen human…

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Computational Biology Software Professional Market 2022 Growth Barriers

The appraisal centre around the world Computational Biology Software Professional market presents an extensive assessment of latest things, market size, drivers, logical entrances, difficulties, and issues as well as key market fragments. Further, in the Computational Biology Software Professional market report, different definitions and plan of the business, applications and…

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ggplot2 – Issue in creating polygon in ggplot in R

Why does my polygon look like two triangles instead of a box? Can some help explain how I can turn the polygon into a box? data <- structure(list(AREA = c(“a”, “a”, “b”, “b”), Lat = c(43.68389835, 43.68389835, 44.3395883, 44.3395883), Long = c(-88.22909367, -88.99888743, -88.22909367, -88.99888743)), row.names = c(NA, -4L), spec…

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r – How to plot in time series with ggplot, geom_line, with line group by ‘answer’

I have plotted this time series data that contains three variables: date, answer, and counts. I would like to plot in time series where the lines representing categories of the answers. I have tried this codes below, but result are not as expected: I did’t get any line. Could anyone…

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‘info jupyterhub’ displays the manpage although it suggests ‘info’ to get the full doc

Package: jupyterhub Version: 2.0.0+ds1-2 Severity: normal X-Debbugs-Cc: gkni…@australdx.fr Dear Maintainer, ‘man jupyterhub’ ends with: > The full documentation for jupyterhub is maintained as a Texinfo manual. If the info and jupyterhub programs are properly installed at your site, the command > info jupyterhub > should give you access to the complete manual. although…

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Bucket List | Devpost

Inspiration Help people handle finances during a massive inflation issue. What it does Helps people handle their money with bucket budgeting. How we built it Using react for our FE and golng for our backend, using openapi to generate frontend client. Challenges we ran into Openapi did not work well…

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Unsure how to run FastQC on interactive node : bioinformatics

Hi all. My goal has long been to get involved in biology-problems — especially in the biomedical realm, but I haven’t had a direct path to doing so because I don’t love “doing” biology itself. For instance, I did a BS and MS in applied math with a healthy dose…

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Brawl breaks out outside ‘Squad’ congresswomen rally

Two protestors at an event at the Somerville Theatre featuring the progressive ‘squad’ congresswomen were involved in a brawl Saturday afternoon with four other men. One video of the incident shows four men approach the protestors, identified as Richard Cadigan-McCarron and Shawn Nelson, just after 4 p.m. and the camera…

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Paris Gilton closed the fashion show at the extravagant spring cloth

Peris Gilton took part in the Milan fashion fashion as a model. But more, she shrugged off the show in the image of the intended one, which is the most prestigious exit of the show. The first ce bula was named unconventionally. Legendary bіlyavka, specialization of the crazy glamor of…

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An Integrated Workflow of Identification and Quantification on FDR Control-Based Untargeted Metabolome

We constructed an untargeted metabolomic workflow that integrated XY-Meta and metaX together. In this protocol, we displayed how to use XY-Meta to generate a decoy spectral library from open access spectra reference, and then performed FDR control and used the metaX to quantitate the metabolites after identifying the metabolomics spectra….

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Addgene: pLKO5-SgHottip-GFP-CRISPRa

These plasmids were created by your colleagues. Please acknowledge the Principal Investigator, cite the article in which the plasmids were described, and include Addgene in the Materials and Methods of your future publications. For your Materials & Methods section: pLKO5-SgHottip-GFP-CRISPRa was a gift from Suming Huang (Addgene plasmid # 134990…

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Engineered LwaCas13a with enhanced collateral activity for nucleic acid detection

doi: 10.1038/s41589-022-01135-y. Online ahead of print. Jie Yang #  1 , Yang Song #  2   3 , Xiangyu Deng  4 , Jeffrey A Vanegas  1 , Zheng You  1 , Yuxuan Zhang  2   3 , Zhengyan Weng  2   3 , Lori Avery  5 , Kevin D Dieckhaus  6 , Advaith Peddi  4 , Yang Gao  7 , Yi Zhang  8…

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6 weird food myths that just won’t die

I’ve been noticing a theme on food TikTok lately. There are, of course, hundreds of myths and misconceptions regarding food that are perpetuated all over social media every single day. That’s nothing new, but there are several that, despite being debunked time and time again, just won’t die. They’ve basically…

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Gene Knockdown Market by Latest Trend, Growing Demand and Technology Advancement 2022-2028

“ Gene Knockdown Market” 2020 analysis reports provide a significant wellspring of fast information for business strategists and based examination. It provides the Gene Knockdown business inspection with advancement analysis and the peak value, the income, petition and supply info. Real makers Evaluation of Gene Knockdown Market. Request Sample Copy…

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Is averaging the loss the same as averaging the gradient in PyTorch?

I understand that a main motivation for updating our networks via batches (or mini-batches) is that PyTorch is able to update using the average gradient found from all losses in the batch. This then makes the distinction between “averaging the gradient” and “averaging the loss,” but leaves me a bit…

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There Are New FDA Safety Warnings About Breast Implants. Here’s What We Know : ScienceAlert

The US Food and Drug Administration (FDA) is now warning that breast implants filled with either silicone or saline may, on rare occasions, give rise to cancer in the scar tissue around breast implants. The safety notice was published this month and is based on an extensive review of the…

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Genetic footprints of assortative mating in the Japanese population

Study cohort description We used data on a total of 172,270 individuals of Japanese and East Asian ancestry. Of these, data on 165,098 individuals were obtained from BBJ, which has enrolled ≥200,000 participants to date. BBJ is a multi-institutional hospital-based genome cohort that collected participants affected with at least one…

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Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation

Martincorena, I. et al. Somatic mutant clones colonize the human esophagus with age. Science 362, 911–917 (2018). CAS  PubMed  PubMed Central  Google Scholar  Yizhak, K. et al. RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues. Science 364, eaaw0726 (2019). CAS  PubMed  PubMed Central  Google Scholar  Yokoyama, A….

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Manually adding genes of interest to transcriptome for RNASeq DE?

Manually adding genes of interest to transcriptome for RNASeq DE? 1 I have been given some RNASeq reads by a collaborator and have been asked to assess whether there is differential expression between treatments in 6 genes of interest to my collaborator. Unfortunately, this is a non-model organism and so…

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Plastomes of limestone karst gesneriad genera Petrocodon and Primulina, and the comparative plastid phylogenomics of Gesneriaceae

Features of the newly sequenced Petrocodon and Primulina plastomes Sizes of the nine newly sequenced plastomes of Petrocodon and Primulina range from 152,323 bp in Pr. medica (D.Fang ex W.T.Wang) Yin Z.Wang to 153,786 bp in Pr. cordata Mich.Möller & A.Weber (Tables 1, S1). These nine plastomes display the typical quadripartite structure…

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Removal of rRNA from Deproteinized, Phenol-Extracted Total RNA by Hybrid Selection

Adapted from RNA: A Laboratory Manual by Donald C. Rio, Manuel Ares Jr, Gregory J. Hannon, and Timothy W. Nilsen. CSHL Press, Cold Spring Harbor, NY, USA, 2011. Abstract In this protocol, rRNAs are selectively removed from a total RNA sample by hybridizing the rRNAs to complementary biotinylated oligodeoxynucleotides that…

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Ten challenges for clinical translation in psychiatric genetics

Pardinas, A. F. et al. Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nat. Genet. 50, 381–389 (2018). CAS  PubMed  PubMed Central  Article  Google Scholar  Stahl, E. A. et al. Genome-wide association study identifies 30 loci associated with bipolar disorder. Nat. Genet. 51,…

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How to use Scikit-Learn in Python [Complete Tutorial]

In this tutorial, we will focus on Scikit-Learn library usage in Python. Scikit-Learn is simple, fast and useful library used in python machine learning. It provides simple and efficient tools used in data analysis and data mining. Its free, easy to use and accessible to everyone. It is reusable in…

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HISAT2 and HTSEQ command

HISAT2 and HTSEQ command 0 @4fedfa78 Last seen 10 hours ago Japan Hello, For analysis of the data by rna-sequencing I selected HISAT2 and HTSeq-count for mapping and counting the genes levels, the libraryLayout is paired, I am using the below command for both but the results are not exact…

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Aged neurons generated directly from skin more accurately model Parkinson’s disease

Induced dopaminergic neurons directly reprogrammed from the skin cells of a patient with idiopathic Parkinson’s Disease. Credit: Janelle Drouin-Ouellet, University of Montreal, Canada The possibility to make virtually all cell types of the human body from induced pluripotent stem cells (iPSCs), which are embryonic-like cells generated from a patient’s skin,…

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Global Fibroblast Growth Factor Receptor 2 market key industry players and their market scope 2022

Pune, Maharashtra, India, September 22 2022 (Wiredrelease) Marke.biz–:The research provides the Global Fibroblast Growth Factor Receptor 2 Market aims at leveraging the insights and perspectives derived based on both qualitative and quantitative data evaluations for the forecast period, 2022-2030. The use of the technology for malady wipeout through direct correction of disturbances…

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Electrochemistry Analysis of Drugs Summarized in Lenvatinibdextrins

Therefore, these systems generally have to have a advanced level involving computational sources as well as run-time, which usually boosts as the difficulty along with the size the information sets. It is known that computational charges are mainly due to continuing assessment technique of the guidelines and also the men…

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ACENET Basics: Job Scheduling with Slurm Tickets, Fri, 23 Sep 2022 at 10:00 AM

This session teaches participants how to use the Digital Research Alliance of Canada’s queuing environment on the national systems, using the job scheduler Slurm. Learn how the scheduler works, how it allocates jobs, what are reasonable requests to minimize wait time, how to make the best use of the resources…

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Diversity and transmission of koala retrovirus: a case study in three captive koala populations

KoRV genetic diversity Illumina env amplicon deep sequencing was carried out on genomic DNA isolated from the peripheral blood mononuclear cells (PBMCs) of 64 koalas housed in three captive koala colonies within Australia, one in South-East Queensland (SE QLD; colony C, n = 33) and two in Sydney, New South Wales (NSW;…

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RefSeq release 214 is available! – NCBI Insights

RefSeq release 214 is now available online, from the FTP site, and through NCBI’s Entrez programming utilities, E-utilities. This full release incorporates genomic, transcript, and protein data available as of September 12, 2022, and contains 328,588,569 records, including 239,609,016 proteins, 47,387,931 RNAs, and sequences from 123,394 organisms. The release is provided in…

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r – Feature Standardize in AutoML H2O

I’m wondering how to standardize features when using h2o‘s AutoML with deep learning and GLM algorithms. Seems it is supported to deep learning and GLM models (docs.h2o.ai/h2o/latest-stable/h2o-docs/data-science/algo-params/standardize.html), but in h2o.automl it does not accept the standardize = TRUE argument. My questions are: Does autoML automatically scales (i.e. standardizes) the features…

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Remains buried in Romania identified as Kansas airman killed during WWII

WICHITA, Kan. (KWCH) – The Defense POW/MIA Accounting Agency (DPAA) on Tuesday announced remains of a 23-year-old U.S. Army Air Forces staff sergeant from Seneca, Kansas were accounted for in July. The DPAA said the remains of Staff Sgt. Moses F. Tate were buried in Romania. “In the summer of 1943,…

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GENEWIZ from Azenta | FragmentGENE

  Gene Fragments are double-stranded, linear DNA fragments of 100-3,000 bp, which are a convenient option due to their faster delivery time, lower cost, and greater flexibility. These fragments are synthesized with the same industry-leading proprietary technology that Azenta Life Science has developed for standard gene synthesis products. We provide…

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LJ with wca in same input script – LAMMPS Beginners

Gokul September 21, 2022, 5:26am #1 Dear Lammps Users, I have a quick question regarding implementing WCA potential (shifted lj) with lj potential in lammps. I have three types of atoms: type-1, type-2, and type-3. I want lj interaction between type-2 and type-3 and WCA interaction between all others. pair_style…

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biopython – Parsing a gene bank file and outputting specific feature information to a csv using Bio Python

So I am trying to parse through a gene bank file, extract particular feature information and output that information to a csv file. The example gene bank file looks like this: SBxxxxxx.LargeContigs.gbk LOCUS scaffold_31 38809 bp DNA UNK 01-JAN-1980 DEFINITION scaffold_31. ACCESSION scaffold_31 VERSION scaffold_31 KEYWORDS . SOURCE . ORGANISM…

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Bioconductor – SNPlocs.Hsapiens.dbSNP155.GRCh37 (development version)

DOI: 10.18129/B9.bioc.SNPlocs.Hsapiens.dbSNP155.GRCh37     This is the development version of SNPlocs.Hsapiens.dbSNP155.GRCh37; to use it, please install the devel version of Bioconductor. Human SNP locations and alleles extracted from dbSNP Build 155 and placed on the GRCh37/hg19 assembly Bioconductor version: Development (3.16) The 929,496,192 SNPs in this package were extracted from…

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Enterprise Solutions

Enterprise Solutions Skip to main content ENTERPRISE SOLUTIONS MISSION On-site Desktop Support Provides on-site and/or remote troubleshooting of, and support for, technological equipment for various departments under the Offices of The President Support deployments of new hardware, data-wiping salvaged equipment, and assist users with configuration of the new systems Systems…

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Multiple conditions DESeq2

Multiple conditions DESeq2 1 Hi, I am working on differentially expressed genes analysis of RNA-seq data extracted from multiple but related experiments: experiment DESH21_E DESH40_S DESN21_E DESN21_S DESN40_E DESN40_S ES21_E ES21_S ES40_E ES40_S where, DES and ES are different in vitro cells; 21/40 are concentration (low/high), and H/N are additional…

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Transformation of Escherichia coli by Electroporation

Abstract Preparing electrocompetent bacteria is considerably easier than preparing cells for transformation by chemical methods. Bacteria are simply grown to mid-log phase, chilled, centrifuged, washed extensively with ice-cold buffer or H2O to reduce the ionic strength of the cell suspension, and then suspended in an ice-cold buffer containing 10% glycerol….

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Postdoctoral Research Fellow in Molecular Biology job with QUEENS UNIVERSITY BELFAST

Job description The School of Medicine, Dentistry & Biomedical Sciences (MDBS) at Queen’s University Belfast, is currently seeking to appoint an exceptional candidate to the post of Postdoctoral Research Fellow. The Tiwari Lab (www.tiwarilab.com) is looking for a Postdoctoral Research Fellow in Molecular Biology. Our team works on employing functional genomics…

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Postdoctoral Scientist – Bioinformatics and Integrative Genomics Research Cluster at Cedars-Sinai

Responsibilities Requisition # 20002022A At Cedars-Sinai, postdoctoral scientists and other junior researchers fulfill a critical role in expanding the horizons of medical knowledge through biomedical research. By hosting more than 100 postdocs, who conduct vital research and receive advanced training with expert faculty mentors, Cedars-Sinai supports the ongoing medical education process that continues…

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Oligonucleotide Pool Library Market Incredible Possibilities, Growth Analysis and Forecast To 2028

The research literature of Oligonucleotide Pool Library market consists of vital information regarding the growth stimulants, challenges, and other prospects which are shaping the business trends over the period of 2022-2028. According to seasoned experts, the market is expected to exhibit a CAGR of XX% over the…

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World-class translational project enters BioInnovation Institute’s Bio Studio program as part of collaboration with Imperial College London

World-class translational project enters BioInnovation Institute’s Bio Studio program as part of collaboration with Imperial College London   COPENHAGEN, Denmark, September 21, 2022 – BioInnovation Institute (BII), an international commercial, non-profit foundation incubating and accelerating world-class life science research, announces today that it has entered a collaboration with Imperial College London…

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Visualization of Pool-HMM results

Visualization of Pool-HMM results 0 Hello everyone, I have run the Pool-HMM tool on my pool-seq data and got final results in this format Chr Start End Pool-HMM 1 312212 413291 11.60071199 1 595314 676207 11.40558651 1 3136358 3180593 11.65338609 1 3788166 3813896 4.561544648 1 5202297 5218014 1.620942559 1 5448808…

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How new COVID-19 vaccines work

; DAY New vaccines against COVID-19 begin to be authorized around the world. How do they work, who makes them? Update on these new serums.  Adaptation to the evolution of viruses The virus of the disease COVID-19, SARS-CoV-2 , has the ability to mutate, like other viruses. It is a…

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Immuno Cure BioTech acquires Shanghai Teresa Healthcare | Taiwan News

Integrating Electroporation Technology & DNA Vaccine Platforms HONG KONG SAR – Media OutReach – 20 September 2022 – Immuno Cure BioTech, a clinical stage biotechnology group based in the Hong Kong Science Park specialising in DNA vaccines and immunotherapies, announced today the acquisition of 92.6% of Shanghai Teresa Healthcare, the…

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Services Australia to scale up neurodiversity hiring program – Training & Development

Services Australia is set for a major expansion of its neurodiversity recruitment program with up to 70 new IT and digital roles to be offered, more than double the number of hires made over the program’s entirety. The Aurora neurodiversity program, run in partnership with Specialisterne Australia, had previously placed…

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Senior/Junior Postdoctoral fellow in Bioinformatics

Highly motivated candidates are invited to apply for a 2-year postdoctoral position (with the possibility of an extension) in the laboratory of Assoc. Professor David Gomez-Cabrero in the Biological and Environmental Sciences and Engineering (BESE) Division at the King Abdullah University of Science and Technology (KAUST) (www.kaust.edu.sa/en/study/faculty/david-gomez-cabrero). The project investigates…

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Job – Principal Biostistician/Bioinformatics job at Kenya Medical Research

Vacancy title: Principal Biostistician/Bioinformatics [ Type: FULL TIME , Industry: Research , Category: Research ] Jobs at: Kenya Medical Research – KEMRI Deadline of this Job: 06 October 2022   Duty Station: Within Kenya , Kisumu , East Africa SummaryDate Posted: Tuesday, September 20, 2022 , Base Salary: Not Disclosed…

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GenScript, Avectas Partner on Cell Therapy Manufacturing

NEW YORK – GenScript and Ireland’s Avectas said on Tuesday that they’re partnering to develop a non-viral cell therapy manufacturing process. Under the terms of the agreement, their research teams will apply Avectas’ Solupore technology to permeabilize target cell membranes to deliver GenScript’s GenCRISPR single guide RNA, CRISPR-Cas9 protein, and GenExact…

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Scientific Visitor Programme and Training Lead Job in European Molecular Biology Laboratory

Job Description TrainingEMBL Heidelberg The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organisations in the world aimed to explore the secrets of life. EMBL integrates 27 members states and currently employs approx. 1 800 people across its six sites in Heidelberg, Barcelona, Grenoble, Hamburg,…

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Subset row-entries according to a list

Subset row-entries according to a list 1 Hello! I want to subset a selected dataset (a list of entries) from a big data file. I have a list named “contig.list” that looks like this: Contig_339241_4 Contig_1004621_3 Contig_1666_1 Contig_836268_32 Contig_1479_10 Contig_640297_1 Contig_365838_1 .. I want to subset the entries of this…

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maker-cbr3_scaffold1-snap-gene-2.37-mRNA-1 | HWG

Performed on: 2013-01-01 Details: Chinese Chestnut Disease Resistant QTL Region (blastx against TrEMBL) Display provided by the neXtProt Feature Viewer Show Results Table BLAST of maker-cbr3_scaffold1-snap-gene-2.37-mRNA-1 vs. UNIPROT/TREMBL Match Name: M5Y1V6_PRUPE Description: M5Y1V6_PRUPE HSP 1 Score: 1135.55 bits (2936), Expect = 0.000e+0Identity = 605/921 (65.69%), Postives = 697/921 (75.68%), Query…

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Pet dogs given anti-rabies vaccine amid the rise in dog-bite cases

Kerala government started injecting rabies vaccine to all pet dogs. There have been 21 deaths due to rabies in the state so far this year. State government has asked people to register their pet dogs. There has been a 57 per cent increase in the use of the anti-rabies vaccine…

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Institut Pasteur de Dakar hiring Bioinformatics Analyst in Dakar, Senegal

We are looking for an enthusiastic and motivated bioinformatician to join the Epidemiology, Clinical Research, and Data Science department at the Institut Pasteur de Dakar. The selected candidate will develop and apply bioinformatics methods to support multiple projects in the area of next-generation sequencing and -omics. Minimum qualification Bachelor’s degree…

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Post-Doctoral Associate in the Division of Science Biology, Dr. Fabio Piano job with NEW YORK UNIVERSITY ABU DHABI

Description Our laboratory at New York University Abu Dhabi is expanding our expert team working on molecular networks and analysis of bioactive molecules in animal development using C. elegans. We use muti-disciplinary approaches to uncover mechanisms underlying fundamental biomolecular and biochemical processes during embryonic development.  A long standing interest in the laboratory has…

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The Global CRISPR Market Evaluated to Surge at $4521.76 Million

CRISPR Market A recent study by Triton Market Research titled ‘Global CRISPR Market’ includes the Global Analysis and Forecasts by Industry Verticals (Therapeutics and Drug Discovery, Biological Research, Agricultural Biotech, Industrial Biotech), Application (Genome Editing/Genetic Engineering, Cell Line Engineering, CRISPR Plasmid, Human Stem Cells, gRNA Database/Gene Library), Product (Designing Tools,…

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DE analysis with multiple factors

DE analysis with multiple factors 0 Hi all, I’m using DEP R package to perform analysis (including DE analysis) on proteins across different conditions bioconductor.org/packages/devel/bioc/vignettes/DEP/inst/doc/DEP.html The package uses limma for DE analysis My experiment is structured as : sample – disease_state( disease / healthy) – environment (env1 / env2) I…

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Vaccines used to prevent monkeypox

The monkeypox virus is a DNA virus that belongs to the Orthopoxvirus genus. This genus comprises other viruses such as camelpox, cowpox, raccoonpox, skunkpox, variola, and vaccinia. While monkeypox was initially discovered in 1958 in monkeys, rodents are known to be its natural reservoir, and humans and other primates are often incidental…

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Electroporation Protocol Bio Rad Gene Pulser

Unit will be tested before shipping. Rad Gene Pulser different transformations. We autoclave the Freezing Mix and store at room temperature. No limit on the number of engaged members from Commun. It is not necessary to incubate DNA with cells. We have a large inventory of equipment, components and parts…

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Bioinformatics job in Riyadh

Riyadh, Saudi Arabia Center for Genomic Medicine Full time The Center for Genomic Medicine (CGM) plans to expand its IT and bioinformatics teams with experts who will be responsible for maintaining the bioinformatics IT infrastructure and developing, maintaining, and execution of computational pipelines…

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Scientist* Bioinformatics & Statistics | datacareer.de

Mainz Work experience Research, development, teaching Become a member of the BioNTech Family! As a part of our team of more than 2.500 pioneers, you will play a key role in developing solutions for some of the most crucial scientific challenges of our age. Within less than a year, we…

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Low expression of key transcripts in scRNAseq dataset after deeper sequencing

Low expression of key transcripts in scRNAseq dataset after deeper sequencing 1 I am having an issue with my single cell data set. This alert was shown after I requested additional reads per cell to be incorporated with the initial data we received. We have previously performed single cell on…

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Nasal Covid Vaccines To Be A Game-changer: Scientists

Share Tweet Share Share Email In mice, a prospective COVID-19 vaccination that is administered by the nose shows promise. One day you might only need to scent to protect yourself from COVID-19. Professors of radiology Ramasamy Paulmurugan and Tarik Massoud are leading an…

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Gritstone bio Cambridge, MA Jobs September, 2022 (Hiring Now!)

Senior Scientist, bioinformatics Gritstone Bio, Inc. Senior Bioinformatics Scientist Job in Cambridge, MA Gritstone Oncology is a public, next-generation personalized cancer and infectious immunotherapy company. Gritstone brings together distinguished scientific founders, an experienced and diverse management team, a seasoned and successful board of directors and deep financial backing to tackle…

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Staff Scientist Bioinformatics – Thermo Fisher Scientific

Job Profile: Staff Scientist, Bioinformatics Location: South San Francisco, California, US Job ID: 205404BR Date Posted: 19 Sept. 2022 Job Overview When you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our…

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Research Analysts Offer Predictions for CRISPR Therapeutics AG’s Q3 2022 Earnings (NASDAQ:CRSP)

CRISPR Therapeutics AG (NASDAQ:CRSP – Get Rating) – Equities researchers at Zacks Research issued their Q3 2022 earnings per share estimates for CRISPR Therapeutics in a report released on Wednesday, September 14th. Zacks Research analyst S. Ganoria anticipates that the company will earn ($2.44) per share for the quarter. The…

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Comment: How to resolve a ValueError: Multiple 'HD' Lines are not permitted when I run Ci

I tried your suggestion **samtools view -H qname_unknown_circle.bam** and the output result is like this: yu@root:~$ samtools view -H qname_unknown_circle.bam @HD VN:1.5 SO:queryname @SQ SN:chr1 LN:248956422 @SQ SN:chr10 LN:133797422 @SQ SN:chr11 LN:135086622 ………(Many lines like this ‘@SQ SN:chrxx LN:xxxx’ are omitted) @SQ SN:chrY_KI270740v1_random LN:37240 @HD VN:1.5 SO:unsorted GO:query @PG ID:bwa…

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KEGG COMPOUND: C00236

KEGG COMPOUND: C00236     COMPOUND: C00236 Help Entry C00236                      Compound                                Name 3-Phospho-D-glyceroyl phosphate;1,3-Bisphospho-D-glycerate;(R)-2-Hydroxy-3-(phosphonooxy)-1-monoanhydride with phosphoric propanoic acid;D-Glycerate 1,3-diphosphate Formula C3H8O10P2 Exact mass 265.9593 Mol weight 266.0371 Structure Mol fileKCF fileDB search Reaction Pathway map00010   Glycolysis / Gluconeogenesis map00710   Carbon fixation in photosynthetic organisms map01060   Biosynthesis of plant secondary metabolites map01061   Biosynthesis…

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Needle-free jet injection of novel COVID-19 DNA vaccine shows promise in animal model

In a recent study posted to the bioRxiv* server, researchers at the United States Army Medical Research Institute of Infectious Diseases evaluated the immunogenicity of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) deoxyribonucleic acid (DNA) vaccine, nCOV-S(JET), in rhesus macaques. A previous evaluation of this coronavirus disease 2019 (COVID-19)…

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Set Axis Breaks Of Ggplot2 Plot In R 3 Examples Specify Tick Marks Of Graph Scale X Con Code

Set Axis Limits in ggplot2 R Plot (3 Examples) | Adjust … 5 days ago Modification of Axis Limits with scale_x_continuous. We have basically two alternatives, if … Modification of Axis Limits with coord_cartesian. Another way to widen the axis ranges of … Cutting off Values with Zoom In. In…

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How to Create a GGPlot with Multiple Lines

Load ggplot2 package library(ggplot2) theme_set(theme_minimal()) Data head(economics) ## # A tibble: 6 x 6 ## date pce pop psavert uempmed unemploy ## <date> <dbl> <int> <dbl> <dbl> <int> ## 1 1967-07-01 507. 198712 12.5 4.5 2944 ## 2 1967-08-01 510. 198911 12.5 4.7 2945 ## 3 1967-09-01 516. 199113 11.7…

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Solved You Plan to sequence the following DNA by Sanger

Transcribed image text: You Plan to sequence the following DNA by Sanger sequencing. your reaction includes your sequencing primer (5−1 is on the (8t) and template DNA ( 5−1 end is on the left), dNIPs, buffer, DNA Polymerase and the following fluorescent dINTPs: red ddGTP, green ddATP, and blue ddITP….

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translate-parent for Maven & Gradle

dependency> groupId>cn.org.opendfl</groupId> artifactId>translate-parent</artifactId> version>1.2</version> </dependency> implementation group: ‘cn.org.opendfl’, name: ‘translate-parent’, version: ‘1.2’ implementation ‘cn.org.opendfl:translate-parent:1.2′ implementation(“cn.org.opendfl:translate-parent:1.2″) libraryDependencies += “cn.org.opendfl” % “translate-parent” % “1.2” <dependency org=”cn.org.opendfl” name=”translate-parent” rev=”1.2″/> @Grapes( @Grab(group=’cn.org.opendfl’, module=’translate-parent’, version=’1.2′) ) [cn.org.opendfl/translate-parent “1.2”] ‘cn.org.opendfl:translate-parent:jar:1.2′ Read more here: Source link

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Run fastqc reports for each of the fastq files in:

Run fastqc reports for each of the fastq files in: /data/CompRes/seq_platform_data/ To run the fastqc reports, you can write a script that will execute the following command (edited for you) for each file: fastqc /data/CompRes/seq_platform_data/<inputfastq> -o /home/ASURITE/BIO439/module4/ Then transfer the html files to your local computer and view them, so…

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[100% Discount] Image Recognition for Beginners using CNN in R Studio

You’re looking for a complete Convolutional Neural Network (CNN) course that teaches you everything you need to create an Image Recognition model in R, right? You’ve found the right Convolutional Neural Networks course! After completing this course you will be able to: Identify the Image Recognition problems which can be solved using CNN Models….

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UGC NET 2022 phase 3 exam city intimation slip issued for September 23 exams

UGC NET 2022 phase 3 admit card will be issued soon at ugcnet.nta.nic.in for exams to be held from September 23 to October 14. UGC NET 2022 NEW DELHI: The National Testing Agency (NTA) has issued University Grants Commission National Eligibility Test (UGC NET) 2022 exam city intimation slip for…

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Tricorder Tech: NASA Astrobiology Field Research With A Hand-held X-ray Fluorescence Field Spectrometer

Vanta Hand-held X-ray Fluorescence Field Spectrometer Astrobiology.com Teams from NASA’s Johnson Space Center and NASA’s Goddard Space Flight Center continue to conduct field work as part of this week’s NASA Expeditions in Hawaii. Teams from NASA’s Johnson Space Center and NASA’s Goddard Space Flight Center continue to conduct field work…

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Isolation of Preadipocytes from Broiler Chick Embryos

The present protocol describes a simple method for isolating preadipocytes from adipose tissue in broiler embryos. This method enables isolation with high yield, primary culture, and adipogenic differentiation of preadipocytes. Oil Red O staining and lipid/DNA stain measured the adipogenic ability of isolated cells induced with differentiation media. Primary preadipocytes…

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