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How to interpret bimodal distribution of GC-content for RNAseq and can it be remedied ?

 August 8, 2021

How to interpret bimodal distribution of GC-content for RNAseq and can it be remedied ?

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A colleague of mine have got the following distribution of GC-content for RNAseq.

How to interpret bimodal distribution of GC-content for RNAseq ?
Does it mean some contamination ?
Is there any method to remedy ?

Figure


RNA-Seq


GCcontent


FastQC


RNAseq

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