Center or fix a sample at 0 on PC1 in PCA plot

Center or fix a sample at 0 on PC1 in PCA plot

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We have recently noticed a group that is consistently able to publish PCA plots with their sample of interest seemingly aligned at 0 on PC1 or both PC1 and PC2 . In their methods they only mention that they use the R prcomp() function. We are interested to understand how they might be doing this. Attached is an example plot showing sample X at 0 on both the PC1 and PC2 axis.

Example PCA plot


Bulk


RNA-Seq


PCA

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