How does AlphaFold help drug discovery? : biotech

AlphaFold is awesome and is a step forward in protein structure prediction, but I see many articles claiming that it will help discover better medicines.

How exactly does predicting a protein structure help discover better medicine?

Could someone with experience please explain exactly how it helps?

I know drugs fit into proteins depending on their shape, and then alter their shape/function. Does AlphaFold help with predicting that altered shape? Maybe faster than molecular dynamics simulations?

I thought we usually know the structure of the protein we’re trying to target, experimentally?

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