How To Interpret PLINK’s plink.lasso File

How To Interpret PLINK’s plink.lasso File

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After running PLINK –lasso command with an h2 estimate 0.8, I received a plink.lasso; however, I am a little confused on how that file is supposed to be interpreted.

Here is a sample of the .lasso file:
.Lasso File

And below is PLINK’s .lasso documentation:
Documentation

I understand that h2(heritability) relates to the measure of the influence genes may have on an individual, but how does that relate to the EFFECT column having negative values?

Could anyone clarify?


PLINK


bioinformatics

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