normality assumption for GWAS QT

normality assumption for GWAS QT

0

Hi

Planning to perform GWAS on quantitative trait using linear reg in plink. From my basic knowledge of statistics, i know that the assumption of normality (residuals) should be only approximately true. But i have seen so many papers on GWAS transforming the data for normalization. My personal view is that ” no real data set is perfectly normal”. So do i need to transform my data with the following plot ? So far i have received mixed feedbacks from my group members (some say it’s ok to go ahead with linear reg, while others want the data transformed)

TIA

enter image description here


assumption


GWAS


linear


normality


regression

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