How are the HMM cutoff scores in TIGRFAMs determined?
As indicated in the title, I am wondering how are the HMM cutoff scores in TIGRFAMs determined?
Where did I find the score? (If you search a TIGRFAM accession in the NCBI protein family model database, e.g. TIGR02064.1, you will be directed to another page that displays information about this HMM including the NCBI HMM accession, GO terms, HMM length, sequence cutoff, domain cutoff, etc.)
The cutoffs I was talking about are the sequence cutoff and domain cutoff, which are usually equal. You can then specify this score in the hmmsearch program if you want to search for a protein.
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