How do I determine p-value and fold change for TMM normalized data?

How do I determine p-value and fold change for TMM normalized data?

0

Hi,

I have a TMM normalized data for cancer vs no cancer treatment. This data, however, does not contain p-value or fold change. I want to generate plots such as heatmaps and volcano plots, but I cann’t do it without their p-values and fold changes. I also do not have the raw counts. Is there a way to calculate p-value and fold change for this normalized data. Any help is greatly appreciated.

Thanks.


TMM


P-value


normalization

• 14 views

Read more here: Source link