Bioinformatics Analyst I
Baylor College of Medicine – Houston, TX
Summary
The laboratory of Dr. Cristian Coarfa at Baylor College of Medicine is looking for a Bioinformatics Analyst I who will assist in cancer related multi-omics bioinformatics. The successful candidate will work primarily in prostate cancer, liver cancer, and kidney cancer related analysis, in collaborative projects with the labs of Dr. Cheryl Walker (Molecular and Cellular Biology) and Dr. Salma Kaochar (Medicine). The Bioinformatics Analyst I will analyze and integrate multi-modal molecular signatures in normal human and disease populations using bioinformatics and computational techniques and concepts.
Job Purpose
The Bioinformatics Analyst I will discover and analyze genomic variation in normal human and disease populations using bioinformatics and computational techniques and concepts.
Job Duties
The job will include both deployment and development of state-of-the art analysis pipelines. Analysis will further incorporate advanced data science techniques such as deep learning and classification to identify potential disease drivers or biomarkers, repurposable drugs, and novel clinical associations of molecular profiles.
Adapts, runs and validates multiple omics analysis pipeline: metabolomics, antibody proteomics, bulk and single cell RNA-Seq, epigenomics (ChIP-seq, bisulfite sequencing, DNA methylation arrays), clinical association with variables such as survival and tumor stage.
Ensures that multi-omics data analysis objectives are met as required by project or supervisor. Uses various computational analyses and biological interpretation of results to review existing data and propose improvements. Develops and tests in-house bioinformatics tools.
Reviews existing multimodal omics signatures, publicly available datasets, propose and execute integrative analysis. Interprets results from similarity searches and integration of investigator and publicly available datasets.
Minimum Qualifications
Bachelor’s degree in Genetics, Biology, Bioinformatics, Biostatistics, Computational Biology, Computer Science, or a related field.
No experience.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
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