Karius hiring Senior / Staff Bioinformatics Scientist

About Karius

Karius provides genomic insights for infectious diseases to enable clinicians to make critical treatment decisions.

Job Description

Karius is a venture-backed life science startup that is transforming the way pathogens and other microbes are observed throughout the body.  By unlocking the information present in microbial cell-free DNA, we are aiming to help doctors quickly solve their most challenging cases, providing industry partners with access to the microbial landscape to accelerate biomarker discovery and clinical trials, discover novel microbes, and ultimately reduce patient suffering worldwide. 


Position Summary

We are seeking a candidate to work in a rapid, iterative research environment at the interface of our analytics, molecular biology, and medical teams, and together with our collaborators and partners. You will use rigorous scientific and engineering practices to investigate and develop new components of  Karius’ microbial knowledge base that supports our analytical pipeline and research studies. You will bring together a variety of molecular, taxonomic, phenotypic, and clinical datasets to gain novel insight into the interaction between microbes and disease. The role sits at the heart of where emerging opportunities meet our technology, and a creative and energetic candidate will have the opportunity to influence and shape that future.  


Why Should You Join Us?

Karius aims to conquer infectious diseases through innovations around genomic sequencing and machine learning. The company’s platform is already delivering unprecedented insights into the microbial landscape, providing clinicians with a comprehensive test capable of identifying more than a thousand pathogens directly from blood, and helping industry accelerate the development of therapeutic solutions. The Karius test we provide today is one of the most advanced solutions available to physicians who aim to deliver better care to many otherwise ineffectively treated patients. Our test is the result of some incredible work done by our scientists, statisticians, engineers, and physicians, all driven by the same mission. You, as part of the Karius team, will be able to see how directly your work has a life-changing impact on people, and at scale. 


Reports to: Director, Core Data 


Location: Redwood City, CA


Primary Responsibilities

•  Develop new computational methods and pipelines to bring in, qualify, enhance, and generate insights from the diverse world of molecular and biomedical data.

•  Formulate strategy, roadmapping, execution, and delivery surrounding new data assets.

•  Be the guardian of quality for our internal knowledge base, data assets, and reproducible research.

•  Work closely with the product, engineering, medical, and scientific teams to set our company’s goals and support the development of new products.

•  Partner on building up a strong culture, positioning our teams as a high-throughput, top-quality, collaborative group.


What’s Fun About the Job?

Karius is operating at the edge of what is now known to be possible in infectious disease diagnostics. With that, comes a wave of new and incredible challenges and opportunities. To deliver on that value, you will be tapping into some of the most advanced technologies, architecting and innovating where the current solutions simply don’t suffice. You will get to see how much your work really matters.  


Travel:   No travel required. 


Physical Requirements

Subject to extended periods of sitting and/or standing, vision to monitor and moderate noise levels. Work is generally performed in an office environment.


Position Requirements

•  PhD in computational biology, statistics, physics, genetics, or related fields, or MS with equivalent work experience.

•  2+ years of biotech industry or postdoctoral experience, or equivalent.

•  Publications of investigation and interpretation of biological data.

•  Experience with, and understanding of, statistics and machine learning.

•  Proficiency in working with large-scale datasets.

•  Familiarity and experience with bioinformatics tools, approaches and workflows, particularly those related to next-generation sequencing data analysis.

•  Creativity in generating hypotheses and proposing experiments and analyses to test them.

•  Contributions to open-source software projects, a plus.


Personal Qualifications

•  Passionate, purpose-driven, and excited about Karius’ mission.

•  Excellence at communication and collaboration within a cross-functional team.

•  Detail oriented with exceptional organizational and time management skills.

•  Self-starting mentality and ability to drive results.

•  Comfortable working in an environment which combines both research aspects as well as development.

•  Ability to work effectively and efficiently in a fast paced (startup) environment.  


At Karius, we value a diverse and inclusive workplace and provide equal employment opportunity for all applicants and employees and are committed to honor and invest in the full diversity of people, in our hiring, recruiting and development of employees across the Company.  All qualified applicants for employment are encouraged to apply and will be considered without regard to an individual’s race, color, sex, gender identity and gender expression (including transgender individuals who are transitioning, have transitioned, or are perceived to be transitioning to the gender with which they identify), religion, age, national origin or ancestry, citizenship, physical or mental disability, medical condition, family care status, marital status, domestic partner status, sexual orientation, genetic information, military or veteran status, or any other basis protected by federal, state or local laws. If you are unable to submit your application due to a disability, please contact us at recruiting@kariusdx.com and we will accommodate qualified individuals with disabilities.    

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