•
Tandem repeat
•
Interspersed
•
SINES and LINES
•
Highly repetitive – _______________
•
Satellite DNA
•
Centromeres and telomeres
•
Part II: organelle DNA
Mitochondrion and chloroplast structure
•
The endosymbiotic theory
•
Inheritance patterns of mtDNA and cpDNA
•
Uniparental inheritance
•
Maternal –
•
Paternal –
•
Replicative segregation
•
Heteroplasmy –
•
Replicative segregation – next slide
•
Result of this?
•
Myoclinic epilepsy and ragged fiber syndrome (MERRF).
•
petite
mutants in yeast show defects in mtDNA
•
Worked problem, page 313
•
Mitochondrial DNA
•
Complexed with _______________ proteins
•
Animals and fungi
•
_________________________
•
Plants
•
___________________________________________________
•
mtDNA genes:
•
1
•
2
•
3
•
4
•
5
•
Human mitochondria DNA
•
Yeast and angiosperm mtDNA
•
Evolution and mtDNA
•
Evolution of mtDNA
•
Rate –
•
Why?
•
Why study evolution using mtDNA?
•
Size and abundance
•
Evolution –
•
Inheritance –
•
Recombination –
•
Out of Africa hypothesis
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