Bioconductor – Melissa

DOI: 10.18129/B9.bioc.Melissa  

 

This package is for version 3.9 of Bioconductor;
for the stable, up-to-date release version, see
Melissa.

Bayesian clustering and imputationa of single cell methylomes

Bioconductor version: 3.9

Melissa is a Baysian probabilistic model for jointly clustering and imputing single cell methylomes. This is done by taking into account local correlations via a Generalised Linear Model approach and global similarities using a mixture modelling approach.

Author: C. A. Kapourani [aut, cre]

Maintainer: C. A. Kapourani <kapouranis.andreas at gmail.com>

Citation (from within R,
enter citation("Melissa")):

Installation

To install this package, start R (version
“3.6”) and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("Melissa")

For older versions of R, please refer to the appropriate
Bioconductor release.

Documentation

To view documentation for the version of this package installed
in your system, start R and enter:

browseVignettes("Melissa")

 

Details

biocViews Bayesian, Clustering, Coverage, DNAMethylation, Epigenetics, FeatureExtraction, GeneExpression, GeneRegulation, Genetics, ImmunoOncology, KEGG, RNASeq, Regression, Sequencing, SingleCell, Software
Version 1.0.0
In Bioconductor since BioC 3.9 (R-3.6) (
License GPL-3 | file LICENSE
Depends R (>= 3.5.0), BPRMeth, GenomicRanges
Imports data.table, parallel, ROCR, matrixcalc, clues, ggplot2, doParallel, foreach, MCMCpack, cowplot, magrittr, mvtnorm, truncnorm, assertthat, BiocStyle, stats, utils
LinkingTo
Suggests testthat, knitr, rmarkdown
SystemRequirements
Enhances
URL
Depends On Me
Imports Me
Suggests Me
Links To Me
Build Report  

Package Archives

Follow
Installation
instructions to use this
package in your R session.


Read more here: Source link