Automatic Outlier Detection for RNA-seq data

Automatic Outlier Detection for RNA-seq data

2

Hi all,

So I am looking for an automated approach to detect outliers in RNA-seq data. I usually looked at a PCA plot and decided visually. Now I would like to automate this. So I have been looking at the PcaHubert() function in rrcov package, which then flags suspected outliers as false:

pca <- PcaHubert(t(rna.data)) 
outliers <- which(pca@flag=='FALSE')

Would this be a good option? Or are there others better suited for RNA-seq data?

Thanks for your input!


RNA-Seq


outlier


rrcov

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