Comparing two RNA-seq data sets mouse and human

Hi
I have a question. We have two RNA-Seq data sets one from mouse and one from human for our gene modification, and we wanted to know how similar they are from each other. I know i can convert the mouse gene names to human orthology using tools like Biomat, but how to compare between the two sets after? Do i use Wilcoxon test? Or rank the LogFC and use spearman correlation? Or i merge the two data sets based on gene names??
Thanks for the help!!