KEGG ENZYME: 2.7.7.78

Entry

EC 2.7.7.78                 Enzyme

Name Class

Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
BRITE hierarchy

Sysname

GDP:alpha-D-glucose 1-phosphate guanylyltransferase

Reaction(IUBMB) Reaction(KEGG) Substrate Product Comment

The enzyme may be involved in prevention of misincorporation of glucose in place of mannose residues into glycoconjugates i.e. to remove accidentally produced GDP-alpha-D-glucose. Activities with GDP-L-galactose, GDP-D-mannose and UDP-D-glucose are all less than 3% that with GDP-D-glucose.

History

EC 2.7.7.78 created 2011

Orthology

K15630

GDP-D-glucose phosphorylase

Genes

HSA:	390637(GDPGP1)

PTR:	745569(GDPGP1)

PPS:	100982804(GDPGP1)

GGO:	101152503(GDPGP1)

PON:	100444173(GDPGP1)

NLE:	100594834(GDPGP1)

MCC:	701954(GDPGP1)

MCF:	102121174(GDPGP1)

CSAB:

103231172(GDPGP1)

CATY:

105592385(GDPGP1)

 » show all
Taxonomy Reference

  Authors

Adler LN, Gomez TA, Clarke SG, Linster CL

  Title

A novel GDP-D-glucose phosphorylase involved in quality control of the nucleoside diphosphate sugar pool in Caenorhabditis elegans and mammals.

  Journal   Sequence Other DBs

ExplorEnz – The Enzyme Database:

2.7.7.78

IUBMB Enzyme Nomenclature:

2.7.7.78

ExPASy – ENZYME nomenclature database:

2.7.7.78

BRENDA, the Enzyme Database:

2.7.7.78