Calculate z-scores from GWAS summary stats
Hello,
I need to calculate the z-scores from meta-GWAS summary stats. The association file has the following header
rs_id Allele1 Allele2 Freq1 Effect StdErr P.value
The ‘effect’ is the Beta coefficent. My understanding is
z-score=Effect/StdErr
Is that correct ? Also, are there any R packages that can do this ?
Many thanks
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