KEGG ENZYME: 3.5.1.12

Entry
EC 3.5.1.12                 Enzyme                                 
Name

biotinidase;
amidohydrolase biotinidase

Class

Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In linear amides

Sysname

biotin-amide amidohydrolase

Reaction(IUBMB)
biotin amide + H2O = biotin + NH3 [RN:R01076]
Reaction(KEGG) Substrate Product Comment

Also acts on biotin esters.

History

EC 3.5.1.12 created 1961

Pathway Orthology Genes

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Reference   Authors

KNAPPE J, BRUEMMER W, BIEDERBICK K.

  Title

[PURIFICATION AND PROPERTIES OF BIOTINIDASE FROM SWINE KIDNEY AND LACTOBACILLUS CASEI.]

  Journal

Biochem Z 338:599-613 (1963)

Reference   Authors

THOMA RW, PETERSON WH.

  Title

The enzymatic degradation of soluble bound biotin.

  Journal

J Biol Chem 210:569-79 (1954)

Other DBs
ExplorEnz – The Enzyme Database:  3.5.1.12
ExPASy – ENZYME nomenclature database:  3.5.1.12

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