VEP for cancer annotation using COSMIC

VEP for cancer annotation using COSMIC

2

Dear all,

I’m struggling in finding how to obtain information about COSMIC database after I annotate a vcf using VEP.
The command that I used is:

vep -i Mutect2_unfiltered_10643_vs_2434.vcf.gz
-o Mutect2_unfiltered_10643_vs_2434_VEP.ann.vcf
–assembly GRCh38
–species homo_sapiens
–offline –cache –cache_version 99
–dir_cache /.vep –everything –filter_common
–fork 4 –format vcf –per_gene –stats_file Mutect2_unfiltered_10643_vs_2434_VEP.summary.html
–total_length –vcf

I get back a vcf annotated file, but I’m not able to find any COSMIC information.
Maybe there is a way to filter only for COSMIC??

Thank you in advance,
Youssef


VEP


COSMIC


Cancer

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