Acting on the aldehyde or oxo group of donors;
With NAD+ or NADP+ as acceptor
pyruvate:NADP+ 2-oxidoreductase (CoA-acetylating)
The Euglena enzyme can also use FAD or methyl viologen as acceptor, more slowly. The enzyme is inhibited by oxygen.
EC 188.8.131.52 created 1989
|pyruvate dehydrogenase (NADP+)|
Inui H, Miyatake K, Nakano Y, Kitaoka S.
Occurrence of oxygen-sensitive, NADP+-dependent pyruvate dehydrogenase in mitochondria of Euglena gracilis.
Inui H, Ono K, Miyatake K, Nakano Y, Kitaoka S
Purification and characterization of pyruvate:NADP+ oxidoreductase in Euglena gracilis.
J Biol Chem 262:9130-5 (1987)
Read more here: Source link