An exciting opportunity has arisen for an Advanced Research Assistant to support the research of the Teichmann faculty in the Cellular Genetics Programme. You will join a dynamic team supporting Teichmann lab projects, including the Human Cell Atlas.
About the team:
Sarah Teichmann is co-founder of the Human Cell Atlas consortium. Our group develops and implements cutting-edge single cell technology combined with human genetics at the cellular level and we apply these methodologies to further our understanding of human health, development and disease. Our current focus includes (but is not limited to) the immune system, heart, lung, gut, muscle and bone. Our studies are primarily of healthy tissue across the lifespan, sometimes with a disease dimension (auto-inflammatory, cancer, infection) as well as in vitro tools for probing mechanisms.
About the role:
You will play a fundamental laboratory-based role within the team, assisting with tissue dissociation to single cells / nuclei and bespoke sequencing library creation for gene expression, immune cell profiling and chromatin accessibility analysis in preparation for downstream NGS analysis.
You will work to test and implement new protocols and scale them up as required, working towards delivering the protocols without requiring close supervision. You will interact with external collaborators to support sample acquisition logistics, sample management and processing and also with our operations teams to submit samples for further analysis. This role requires an out-of-hours component, often at short notice, when tissue samples become available.
Excellent communication and relationship-building skills alongside strong time management and organisational skills are needed as is the ability to troubleshoot and identify areas for process improvement.
This is an excellent opportunity for a motivated and adaptable individual to support the cutting edge science delivered within the Teichmann faculty.
Biological degree with relevant laboratory experience
Experience with tissue dissociation and/or nuclei preparation
Good Laboratory Practice
Ability to test and implement new approaches and techniques
Relevant post-graduate laboratory experience
Significant experience of core molecular biology techniques, including sample handling, PCR, RNA/DNA purification, library prep and similar
Competencies and Behaviours
Ability to organise own workload
Ability to work independently and within a group but be able to recognise when to seek help.
Ability to keep good records
Good written and oral communication skills.
Ability to work to a schedule and successfully manage and prioritise multiple competing projects
Please apply with a CV and a cover letter outlining your suitability for the role addressing the criteria set out above.
Part time Working
We welcome applications for this position that are looking for part time hours and equal consideration will be given to individuals regardless of their working preferences. This can be discussed further at interview stage.
For informal queries, please contact Anna Wilbrey-Clark.
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