Per base sequence content failed in fastQC

Per base sequence content failed in fastQC

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In the fastQC report of my ChiPseq (paired-end, H3k27me3, Sanger / Illumina 1.9, Sequence length: 42), I got failure in Per base sequence content (see figure below), but other fields such as Adapter Content were fine. What does this indicate and any suggestion for pre-processing the data? Many thanks!

I have ChiPseq reads on

Per base sequence content failed
fastQC


fastQC

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