Director, Translational Bioinformatics – Job at Moderna Therapeutics in Cambridge, MA

The Role:
Moderna is seeking a (Senior) Director to join our Oncology Development organization. You will build a team with strong translational bioinformatics capability to support our mission in delivering mRNA-based therapeutics to cancer patients. You will provide scientific, technical, strategic, and managerial leadership to the growing translational and clinical oncology. You will also work collaboratively with other computational groups across the Moderna research ecosystem to bridge clinical and basic research,

Here’s What You’ll Do:

  • Build and lead a team to develop the translational bioinformatics strategy and set priorities

  • Lead the development, deployment, and application of novel algorithms, analyses, and pipelines with translational impact for personalized cancer vaccine program

  • Perform and supervise the analysis, visualization and interpretation of large, complex datasets from oncology clinical trials, especially modern NGS platforms

  • Partner with clinical team to develop biomarker testing strategies, collaborate on genomic biomarker identification, and communicate findings to internal and external stakeholders

  • Integrate different data modalities with clinical observations, and use novel analytical approaches to distill biomarker insights and mechanistic understanding

  • Author and review translational research sections in regulatory documents and scientific publications

  • Establish collaborations and maintain strong partnership with external scientific community and KOLs

Here’s What You’ll Bring to the Table:

  • PhD in a scientific field, minimum 10 years’ experience in a pharmaceutical, biotech, or research organization with direct experience in the field of computational biology and/or bioinformatics.

  • Knowledge of immuno-oncology, clinical and translational science

  • Experience leveraging data from large-scale, open repositories in immune-oncology field and integrating datasets to mine for deeper insights

  • Fluency in Python and R, including packages in the scientific computing stack

  • Experience with software development, including version control, unit and integration testing, documentation, and deployment

  • Experience with high performance computing and cloud computing platforms

  • Track record of productivity and innovation as evidenced by patents and/or publications

  • Outstanding communication skills, especially of conclusions drawn from large, complex datasets

  • Ability to effectively collaborate in a fast-paced, dynamic environment

Here’s What We’ll Bring to the Table:

  • On-site subsidized cafeteria or catered lunches
  • Company-provided iPhone
  • Free parking, monthly subway pass or a subsidized commuter rail pass
  • Free annual corporate membership to Bluebikes
  • Highly competitive healthcare coverage including: medical offered through BCBS (HMO/PPO), dental, and vision offered through VSP
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • 16 weeks of 100% paid parental leave for all new parents
  • 16 weeks 100% paid family caregiver leave
  • 20 weeks 100% paid medical leave
  • Eligible for “Moderna Month” (one month paid sabbatical after five years of service and eligible for additional one month paid sabbatical every 3 years thereafter)
  • Adoption assistance and discounts to local childcare centers, as well as access to
  • 401k (traditional and Roth offered) with 50% match on first 6% deferred. Match is vested immediately
  • A suite of Moderna paid insurance coverage, including: life insurance, short-term and long-term disability
  • Voluntary legal assistance plan
  • 15 days’ vacation and 7 sick days per year, in addition to a discretionary winter shut down and 11 company paid holidays (includes 2 floating holidays)

Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19. Newly hired employees must be vaccinated prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated where it is not an undue hardship to the company to do so as provided under federal, state, and local law.

About Moderna:

In 10 years since its inception, Moderna has transformed from a science research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across six modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for both clinical and commercial production at scale and at unprecedented speed. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna’s capabilities have come together to allow the authorized use of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna’s mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and auto-immune diseases. Moderna has been named a top biopharmaceutical employer by Science for the past six years. To learn more, visit .

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.


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