Senior Scientist, Bioinformatics, Oncology job with AstraZeneca

Do you have expertise in, and passion for Bioinformatics? Would you like to apply your expertise to impact the delivery of sequencing data (NGS) and the delivery of pipelines in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the one for you!

This position can be based in Boston US, Gaithersburg US or Cambridge UK


AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies.A place built on courage, curiosity and collaboration – we make bold decisions driven by patient outcomes. Empowered to lead at every level, free to ask questions and take smart risks that write the next chapter for our pipeline and Oncology team. Make a meaningful impact that brings real benefits to society. By applying your knowledge of data, you will help to redefine our industry and ultimately save lives. Work with experts who share a common goal: to accelerate the potential of medicines and the science of tomorrow.


It’s a business that’s taking data seriously – we’re already on a journey, transforming AstraZeneca into a data-driven enterprise, but the scale of investment behind it shows the importance of Data Science and AI, and the ambition to take that to the next level. We turn insights into reality – from machine learning on molecules to engineering that embeds innovation into how the company works. It’s technically challenging here – there are huge data sets and highly complex databases. You get to be a part of the team that changes AstraZeneca into a data-driven enterprise.

What you’ll do

There is an exciting opportunity for a talented and motivated bioinformatician, eager to bring NGS data together in new ways, to join the group as a Sr. Scientist. In this role, you will:

  • Manages, analyses, and deliver sequencing data (NGS).

  • Develops, tests, and supports data analysis tools and pipelines.

  • Ensure proper automation of data analysis.

  • Build scalable (Cloud and HPC) solutions that work on tens of thousands of CPUs.

  • Validate the quality of the datasets using various tools to assess the correctness of the results.

  • Troubleshoot data quality issues by collaborating with Lab and other personnel.

  • Assist with developing requirements for internal software development.

  • Build and maintain high level of experience with team’s software and IT technologies.

  • Work collaboratively with scientists and outside collaborators to cultivate, process, and analyze genomic information

  • Develop and maintain a in depth understanding of the scientific and technological domains supported by the NGS Informatics team.

  • Design and apply innovative computational/statistical algorithms and visualizations to: Generate actionable biological insight from genomic data.

  • Build and steer further development of small prototype tools for bench scientists to access and visualize genomic data. Finally, you will collaborate with industry and academia, and exploit external resources, to find the most effective solutions to problems.

  • Build and maintain high level of experience with team’s software and IT technologies

Essential for the role

  • Relevant graduate degree: Bioinformatics / Computational biology: Computer Science / Engineering

  • Applied experience in genomics / bioinformatics Sequencing data analysis

  • Solid programming skills in multiple programming languages

  • Experience in software development best practices

  • Experience in Unix

  • Experience in Cloud computing (AWS) and/ or HPC (High Performance Computing)

Desirable for the role

  • Experience in SQL databases, REST APIs

  • An understanding of the contribution of bioinformatics to drug discovery.

  • Awareness of machine learning, graph modeling, Bayesian analytics or other non-traditional approaches to model biological data.

Competitive salary & benefits

Close date: 28th November 2021

Why AstraZeneca?

As a team we are deeply committed to transforming the lives of patients living with cancer – with the ultimate aim of eliminating cancer as a cause of death.

So, what’s next?

  • Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

  • Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it’s yours.

  • If you’re curious to know more then please reach out to Louise Bennett

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn

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“As part of the application process for some roles at AstraZeneca, candidates may be asked to complete a series of online games, created by pymetrics, to assess certain candidate qualities to help evaluate potential match for the position. If the pymetrics process applies to this role, you will receive an email invitation with additional information following application. Once completed AZ will automatically receive your results – pymetrics will not be used solely in our decision-making process but will help us gather additional insight.”

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