Identify most and least abundant allele (nMAJ and nMIN) for pooled heterozygosity (hp) analysis from vcf file
I am trying to calculate Pooled Heterozygosity (hp) by identifying nMAJ and nMIN from vcf file with a sliding window 150kb. I am confused after reading papers where they calculated using formula but no particular method to calculate nMAJ and nMIN. Can you please share the way to calculate the same. I will be grateful to you all.
Hp = 2ΣnMAJΣnMIN/(ΣnMAJ + ΣnMIN)2
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