Deconvolution of RNAseq (bulk) from skin samples
Hello! I have RNAseq data (bulk) from a skin disease, and I would like to do deconvolution. I have understood that for this I need a reference matrix. I found one for skin which is named “Derm22” but the problem here is that this signature matrix is made from microarray data, is that a problem when my gene expression matrix is from RNAseq?
If it is a problem, do anyone know of a reference matrix which contain cells typical in the skin which is from RNAseq?
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