Bioconductor – genomicInstability

DOI: 10.18129/B9.bioc.genomicInstability  

 

Genomic Instability estimation for scRNA-Seq

Bioconductor version: Release (3.14)

This package contain functions to run genomic instability analysis (GIA) from scRNA-Seq data. GIA estimates the association between gene expression and genomic location of the coding genes. It uses the aREA algorithm to quantify the enrichment of sets of contiguous genes (loci-blocks) on the gene expression profiles and estimates the Genomic Instability Score (GIS) for each analyzed cell.

Author: Mariano Alvarez [aut, cre], Pasquale Laise [aut], DarwinHealth [cph]

Maintainer: Mariano Alvarez <reef103 at gmail.com>

Citation (from within R,
enter citation("genomicInstability")):

Installation

To install this package, start R (version
“4.1”) and enter:

if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("genomicInstability")

For older versions of R, please refer to the appropriate
Bioconductor release.

Documentation

To view documentation for the version of this package installed
in your system, start R and enter:

browseVignettes("genomicInstability")

 

Details

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