DOI: 10.18129/B9.bioc.genomicInstability
Genomic Instability estimation for scRNA-Seq
Bioconductor version: Release (3.14)
This package contain functions to run genomic instability analysis (GIA) from scRNA-Seq data. GIA estimates the association between gene expression and genomic location of the coding genes. It uses the aREA algorithm to quantify the enrichment of sets of contiguous genes (loci-blocks) on the gene expression profiles and estimates the Genomic Instability Score (GIS) for each analyzed cell.
Author: Mariano Alvarez [aut, cre], Pasquale Laise [aut], DarwinHealth [cph]
Maintainer: Mariano Alvarez <reef103 at gmail.com>
Citation (from within R,
enter citation("genomicInstability")
):
Installation
To install this package, start R (version
“4.1”) and enter:
if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install("genomicInstability")
For older versions of R, please refer to the appropriate
Bioconductor release.
Documentation
To view documentation for the version of this package installed
in your system, start R and enter:
browseVignettes("genomicInstability")
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