It is possible, but only with a code change in
- If the database is a FASTA file, you could add a new Jackhmmer searcher for that database. You can take a look at the
jackhmmer_uniref90_runnerand basically follow the same logic for your database.
- If the database is a HH Suite database, you could add a new HHBlits searcher for that database. You can take a look at the
hhblits_bfd_uniclust_runnerfor inspiration in this case.
Alternatively, if this is a custom FASTA file, you could try passing that instead of one of the existing databases, e.g. small_BFD or MGnify. Note this might lead to worse results as you would be replacing one database with another.
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