Escherichia coli K-12 substr. MG1655 EC 1.1.1.282

BioCyc ID: RXN-11174

Enzymes and Genes:

The reaction direction shown is in accordance with the direction in which it was curated.

Most BioCyc compounds have been protonated to a reference pH value of 7.3. Please see the
PGDB Concepts Guide for more information.

Mass balance status: Balanced.

Enzyme Commission Primary Name:
quinate/shikimate dehydrogenase [NAD(P)⁺]

Enzyme Commission Synonyms:
YdiB

Standard Gibbs Free Energy (Δ_rG^‘°):
-1.9282227 kcal/mol

Enzyme Commission Summary:

This is the second shikimate dehydrogenase enzyme found in
Escherichia coli. It can use both
L-quinate and
shikimate as substrates and either NAD+ or NADP+ as acceptor. The low catalytic efficiency with both quinate and shikimate suggests that neither may be the physiological substrate. cf
EC 1.1.1.24, quinate/shikimate dehydrogenase (NAD⁺),
EC 1.1.5.8, quinate/shikimate dehydrogenase (quinone), and
EC 1.1.1.25, shikimate dehydrogenase (NADP⁺).

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