Senior Research Associate/Principal Research Associate, Bioinformatics job with Vedanta Biosciences

Title: Senior Research Associate/Principal Research Associate, Bioinformatics

Location: Cambridge, MA, or up to 100% remote

Reports to: Scientist I, Bioinformatics

The Role:

We are looking for a bioinformatician/computational biologist to support the Research and Development team in the maintenance and querying of an existing laboratory information management system (LIMS), construction and maintenance of genomic and metagenomic databases, operation and optimization of existing microbiome analysis and bacterial genomics workflows, development of lab automation programs and new microbiome workflows. In support of the development of Vedanta Biosciences’ portfolio of Live Biotherapeutic Products (LBPs), the candidate will support the characterization of bacterial isolate genomes, develop efficient data storage and processing workflows, and support the processing of metagenomics and amplicon sequencing data. We are looking for an individual who is independent, curious, self-motivated, scientifically rigorous, and excited to collaborate with Vedanta’s diverse team of researchers. The job title and level will correspond to the experience and skills of the selected candidate.

Here’s What You’ll Do:

  • Support the development, curation, and expansion of Vedanta’s database of bacterial genomes and associated metadata.
  • Maintain and query Vedanta’s LIMS backend.
  • Benchmark and optimize cloud-based microbiome analysis workflows.
  • Collaborate with the research team to write wet lab automation programs.

Requirements:

  • BS/MS in bioinformatics, computational biology, or related quantitative field with 2+ years of working experience.
  • 2+ years of experience in Python is required.
  • Database experience with SQL, preferably PostgreSQL, required.
  • Experience with cloud computing infrastructure (Amazon Web Services (AWS) or Google cloud) is required.
  • Analytical experience with microbiome and microbial community ecology datasets is highly desirable.
  • Programmatic experience in the maintenance and querying of LIMS is highly desirable.
  • Experience in the development and operation of reproducible pipelines (e.g. Snakemake or Nextflow, versioning with Git) is desirable.
  • Experience in unit testing, algorithms, or data structures is desirable.
  • Highly organized and motivated individual. Detail oriented. Must be a team player, able to work well in a group setting as well as independently in a fast-paced environment.

Why join Vedanta Biosciences

Vedanta is pioneering the development of a new class of therapies that act by modulating the human microbiome. Modulation of the human microbiota holds enormous promise to treat a broad range of immune and infectious diseases in ways that are completely different to existing drug classes. Breakthrough discoveries of our scientific team in the field of mucosal immunology have led to the first rationally designed drug candidates in the microbiome field. Vedanta was founded by PureTech Health and a team of world-renowned experts in immunology and microbiology.

We invite you to explore our site to learn more about our company and how our discovery platform enables identification of bacterial consortia with drug-like properties and their manufacture to GMP standards.
Our Vision: We are harnessing the human microbiome to enable a new drug modality based on rationally defined bacterial consortia
Vedanta is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Vedanta will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Vedanta Biosciences requires all employees to be fully vaccinated against COVID-19 and newly hired employees must be fully vaccinated prior to their employment start date. Vedanta Biosciences will consider accommodations for individuals who are unable to be vaccinated against COVID-19 due to a qualifying medical condition or disability or a sincerely held religious objection.

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