Comparative Study of PID Control and Model Predictive Control for a Microfluidic Electroporation System – HKUST SPD

Bibliographic Details Author
Ghadami, Mohammad


Shagoshtasbi, Hooman



Mahjoob, Mohammad Jahromi



Lee, Yi-Kuen

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Issue Date 2013 Source The 8th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS 2013), Institute of Electrical and Electronics Engineers (IEEE), 2013, p. 895-898 Abstract This paper describes a comparative study of two feedback control methods for a microfluidic electroporation (EP) system. The regulation of the transmembrane voltage (V-m) and nano-electropore radius (r) of HeLa cells on a micro EP chip was achieved using a linear Proportional-Integral-Derivative (PID) Controller and also Model Predictive Controller (MPC) based on the critical electric field for single-cell EP. Numerical simulations of static and dynamic responses of the two critical states, Vm and r, shows that feedback control can improve the cell viability and EP efficiency compared to open-loop (OL) system. The benefits and limitations of these two control methods for EP and possible future works have also been discussed. Conference 2013 8th IEEE International Conference on Nano/Micro Engineered and Molecular Systems (NEMS), Suzhou, China, 7-10 April 2013 Publisher Institute of Electrical and Electronics Engineers (IEEE) Subject DOI 10.1109/NEMS.2013.6559867 ISBN 9781467363525
9781467363518 Language English Type Conference paper Access View details via DOI
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