Is dropout a big concern (or factor) when analysing single cell RNAseq?

Is dropout a big concern (or factor) when analysing single cell RNAseq?

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When analysing single cell RNAseq is drop-out (% dropout by count) a huge factor that needs to be paid attention?
I see mixed opinions (publications, workshops, etc) on how to deal with dropouts whether to use imputation or not.


single


dropout


cell


scRNA

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