KEGG ENZYME: 1.16.1.1


KEGG ENZYME: 1.16.1.1


KEGG     ENZYME: 1.16.1.1
Entry
EC 1.16.1.1                 Enzyme                                 
Name

mercury(II) reductase;
mercuric reductase;
mercurate(II) reductase;
mercuric ion reductase;
mercury reductase;
reduced NADP:mercuric ion oxidoreductase;
mer A

Class

Oxidoreductases;
Oxidizing metal ions;
With NAD+ or NADP+ as acceptor

Sysname

Hg:NADP+ oxidoreductase

Reaction(IUBMB)
Hg + NADP+ + H+ = Hg2+ + NADPH [RN:R02807]
Reaction(KEGG)
Substrate
Product
Comment

A dithiol enzyme.

History

EC 1.16.1.1 created 1984

Orthology
Genes
STY HCM1.158(merA) HCM1.231c(merA)
SEE SNSL254_p_0165(merA)
ENC ECL_03824(merA) ECL_A045(merA) ECL_A232(merA)
ECLE ECNIH2_24995 ECNIH2_25700
EKB BFV64_17520 BFV64_17570
KPN KPN_pKPN4p07068(merC)
KPX PMK1_ndm00248(merA)
KPB FH42_25750 FH42_26535
KOE A225_1953 A225_R1p0545
KOC AB185_01275 AB185_01990 AB185_02655 AB185_02765 AB185_03195 AB185_03305
KQU AVR78_26650 AVR78_27160
KGR JJJ10_04135 JJJ10_29105
REE electrica_05182(merA_1) electrica_05246(merA_2)
CAMA F384_23575 F384_27190
CFAR CI104_26605(merA) CI104_28660
CIR C2U53_00660 C2U53_02890
KIE NCTC12125_05066(merA)
KAS KATP_46630(merA_1) KATP_47280(merA_2)
LEI C2U54_24595(merA) C2U54_26460(merA)
LEH C3F35_24620(merA) C3F35_26075(merA)
KIN AB182_00550 AB182_01655 AB182_02965
SMAR SM39_pSMC1_10(merA)
PANP PSNIH2_20685 PSNIH2_21720
PSX DR96_1759(merA) DR96_3150(merA)
RHD R2APBS1_1852 R2APBS1_2075 R2APBS1_2097 R2APBS1_3788
PAP PSPA7_0090(merA2) PSPA7_0104(merA1)
PAG PLES_26321 PLES_26871(merA)
PAEB NCGM1900_3722(merA)
PAEL T223_13480 T223_13770
PAEU BN889_06325(merA1_1) BN889_07001(merA1_2)
PPUH B479_00005 B479_27209
PPUD DW66_5840 DW66_5850 DW66_5862
PMAN OU5_P0198(merA) OU5_P0377(merA)
PLUL FOB45_01020 FOB45_01560(merA) FOB45_02680(merA) FOB45_27245(merA) FOB45_27755(merA)
PALK PSAKL28_31270 PSAKL28_31520
PUM HGP31_24395(merA) HGP31_25875(merA)
PHF NLY38_11890(merA) NLY38_15250(merA)
MAQ Maqu_0242 Maqu_1392 Maqu_4010
MARI ACP86_03865 ACP86_18830
MLQ ASQ50_01435 ASQ50_14140
MARA D0851_11865(merA) D0851_16930(merA)
AJO RZ95_18705 RZ95_18765
ADV DJ533_01880(merA) DJ533_01950(merA)
SHN Shewana3_4311 Shewana3_4345
IDT C5610_08055(merA) C5610_10310(merA) C5610_10420
AMC MADE_1005505 MADE_1005590 MADE_1010355
AMAL I607_04755 I607_13895
AMAE I876_04970 I876_14395
AMAO I634_14310 I634_14315
HMI soil367_11370(merA)
CZA CYCME_0209(merA) CYCME_2511(merA2)
APRS BI364_08850 BI364_11010
HAXI HAALTHF_21420n HAALTHF_21430n HAALTHF_53870n
RMN TK49_16515 TK49_16780 TK49_22125 TK49_23235
RME Rmet_2315(merA”) Rmet_6174(merA) Rmet_6183(merA)
CUU BKK79_15685 BKK79_36480 BKK79_37545
AXX ERS451415_01080(merA_1) ERS451415_05778(merA_2)
DTS BI380_10590 BI380_17585
ADN Alide_1826 Alide_4499
ADK Alide2_1949 Alide2_3377
DAER H9K75_19660(merA) H9K75_20055(merA)
DIA Dtpsy_1158 Dtpsy_2133
SIMP C6571_05225(merA) C6571_18275(merA)
THI THI_1799(merA1) THI_3072(merA2)
BBAG E1O_05500 E1O_17540 E1O_18600
NET Neut_0030 Neut_1309 Neut_2567
SULF CAP31_04270 CAP31_14525
SPLB SFPGR_15340(merA_1) SFPGR_28180(merA_2)
RBU PG1C_00355 PG1C_08755
GBN GEOBRER4_06470(lpdA-3)
DVE DESUT3_40230(lpdA-3)
RBS RHODOSMS8_01785(merA) RHODOSMS8_01804(merA)
SFH SFHH103_06267(merA2)
SINO SS05631_a49180 SS05631_a49190
RHT NT26_p10055(merA) NT26_p10165(merA2)
BBET F8237_02455(merA) F8237_18365(merBA) F8237_18440(merBA) F8237_34800(merBA) F8237_34920(merBA)
OCG OCA5_pOC16700650(merA)
OCO OCA4_pOC167B00650(merA)
XAU Xaut_0797 Xaut_2903
AALA IGS74_01025(merBA)
RBM TEF_03200 TEF_11865 TEF_15935
PPHR APZ00_10540 APZ00_15950
LABT FIU93_31185(merA2)
BVY NCTC9239_01538(merA)
OAT OAN307_c17630(merA1) OAN307_c31790(merA2)
MALG MALG_04722 MALG_04770
SINL DSM14862_01694(merA_2)
RMM ROSMUCSMR3_04218(merA)
RID RIdsm_05322(merA_1) RIdsm_05720(merA_2)
LVS LOKVESSMR4R_03884(merA)
SAL Sala_2512 Sala_2683
AMV ACMV_26480(merA) ACMV_P1_00190(merA)
AFE Lferr_0161 Lferr_0162 Lferr_2107
AFI Acife_0787 Acife_2290
ATX GCD22_00075(merA) GCD22_02009(merA) GCD22_02644(merA)
AGN AFK25_03970 AFK25_07380
NTM BTDUT50_05585 BTDUT50_08970
SUW SATW20_00600(merA) SATW20_p1290(merA)
SAUZ SAZ172_0060(merA) SAZ172_p120(merA)
SAUT SAI1T1_10190(merA)
SAUJ SAI2T2_20190(merA)
SAUK SAI3T3_20190(merA)
SAUQ SAI4T8_20190(merA)
SAUX SAI6T6_20200(merA)
SHV AAT16_00055 AAT16_14000
GHA NCTC10459_00148(merA)
PMAR B0X71_08870 B0X71_09110 B0X71_19735
SAG SAG1254(merA-1) SAG2023(merA-2)
SAUP NCTC3168_00588(merA_1)
SURN NCTC13766_01961(merA-1)
SVF NCTC3166_00185(merA_1)
LHO LOOC260_118600(merA)
THEP DYI95_007845(merA)
MKR MKOR_17730 MKOR_34270
MCB Mycch_5491 Mycch_5643 Mycch_5854
MMUC C1S78_014500(merA)
MFLV NCTC10271_02229(merA_2) NCTC10271_02259(merA_3) NCTC10271_02391(merA_5)
CUV CUREI_04380 CUREI_04425
CSTA CSTAT_00445 CSTAT_13190
CMIN NCTC10288_00669(merA)
BFV C628_12370 C628_14895
RHS A3Q41_05014(merA_3)
DIT C3V38_13460(merA) C3V38_17180(merA)
DPC A6048_07940 A6048_11250
DKN NHB83_10635(merA) NHB83_17655(merA)
SGOB test1122_05740(merA)
PSEV USB125703_01388(merA)
ART Arth_1778 Arth_4196 Arth_4296 Arth_4465
ARR ARUE_232p00800(merA)
ARX ARZXY2_4447(merA) ARZXY2_4770(merA)
AAU AAur_pTC10241(merA)
APN Asphe3_40770 Asphe3_41570
PSNI NIBR502771_16605(merA)
KRS EQG70_01705(merA) EQG70_08655(merA)
MICK B1A86_00000800(merA) B1A86_00005355(merA) B1A86_00010255(merA)
CEZ CBP52_06750 CBP52_07530
TES BW730_01890 BW730_15580
TLA TLA_TLA_00567(merA)
RAIN Rai3103_06965(merA)
NRO K8W59_19335(merA) K8W59_19785(merA)
MGG MPLG2_0889(merA) MPLG2_2156(merA)
PBRO HOP40_20280(merA) HOP40_35010(merA)
SACE GIY23_03345(merA) GIY23_12695(merA)
MGOS DIU38_025605(merA)
MOD AS202_15470 AS202_19710
AALG AREALGSMS7_02403(merA)
CGLE NCTC11432_01487(merA)
PTAN CRYO30217_03568(merA)
NMV NITMOv2_1558(merA) NITMOv2_4220(merA)
HLM DV707_09865(merA) DV707_18215(merA)
HLA Hlac_2847 Hlac_2994
HALQ Hrr1229_016225(merA)
HAH Halar_0455 Halar_1060
TVO TVG0264489(TVG0264489)
FAC FACI_IFERC01G1595 FACI_IFERC01G1909
FAI FAD_0574(merA) FAD_0911
SCAS SACC_13730(merA) SACC_23860
AHO Ahos_1711 Ahos_1802
NGA Ngar_c19680(merA1) Ngar_c27380(merA2)
LOKI Lokiarch_15050(merA_1)

 » show all

Reference
  Authors

Fox B, Walsh CT.

  Title

Mercuric reductase. Purification and characterization of a transposon-encoded flavoprotein containing an oxidation-reduction-active disulfide.

  Journal

J Biol Chem 257:2498-503 (1982)

Reference
  Authors

Fox BS, Walsh CT

  Title

Mercuric reductase: homology to glutathione reductase and lipoamide dehydrogenase. Iodoacetamide alkylation and sequence of the active site peptide.

  Journal
  Sequence
Other DBs
ExplorEnz – The Enzyme Database:  1.16.1.1
ExPASy – ENZYME nomenclature database:  1.16.1.1
UM-BBD (Biocatalysis/Biodegradation Database):  1.16.1.1

DBGET integrated database retrieval system

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