How can two contradicted gene sets be enriched in a cancer sample in GSEA analysis?

How can two contradicted gene sets be enriched in a cancer sample in GSEA analysis?

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How can two contradicted gene sets be enriched in a cancer sample in GSEA analysis?
For example in GSEA analysis of cancer sample vs normal sample, How can HALLMARK_UV_RESPONSE_UP and HALLMARK_UV_RESPONSE_DN be enriched in a cancer sample at the same time? What does it mean?


HALLMARK_UV_RESPONSE_UP


GSEA

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