Seeking explanation of the difference between GO term normal vs non-redundant!

Seeking explanation of the difference between GO term normal vs non-redundant!

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Hi people,

I am trying to do some GO analysis (ORA and GSEA) of my RNA-seq data on the WebGestalt website and while choosing a functional database as geneontology, there are options for GO terms as normal and non-redundant (such as Cellular Component and Cellular Component nonRedundant).

Could any of you kindly explain what are the differences between these two and how it affects the result? I have tried both with my data and I see the enriched functions are somewhat different in the result.

Thanks in advance.


GO


RNA-seq


term


analysis


webgestalt

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