Biomedical Specialist – Bioinformatics & Functional Genomics Core at Cedars-Sinai

The Cedars-Sinai Center for Bioinformatics and Functional Genomics (CBFG) is an integrated, interdisciplinary research group established in 2016, with the common goal of developing end-to-end research workflows for genomic and high-throughput functional analysis of patient samples. Led by director, Simon Gayther, PhD, the primary goals of the CBFG are to establish a research nexus that integrates leading-edge developments in computational sciences, next-generation genomics and epigenomics, and to use functional biology to improve our understanding of disease etiology applied to personalized health. To learn more, please visit Bioinformatics & Functional Genomics | Cedars-Sinai.

Are you ready to be a part of breakthrough research?

The CBFG Biomedical Specialist performs DNA/RNA isolation from different sources including cells, tissue, FFPE curls and scrapes, and blood, as well as understands and performs the full NGS workflow, including DNA/RNA quant and QC analysis, manual library preparation, library quant and QC analysis, sequencing on the Illumina platform, and sequencing metrics analysis. The Biomedical Specialist will maintain accurate and up-to-date electronic documentation using an electronic lab notebook, project management software, and laboratory information management system, and manually prep libraries of bulk cell, single cell, and spatial omics, including transcriptomics (RNA-Seq), genomics (WGS/WES), epigenomics (WGBS, ATAC-Seq), and metagenomics (16S/ITS amplicon sequencing, shotgun).

Primary Duties and Responsibilities:

  • Train, guide, and supervise a team of junior associates.
  • Train and supervise junior associates on Next-Generation Sequencing experiments, procedures, and day-to-day service request fulfillment and lab operations.
  • Effectively communicate needs and requirements to junior associates as required for the management of service requests and day-to-day lab operations.
  • Manage junior associate performance, mentor and coach, and seek opportunities to help them grow and become their best.
  • Assign service requests to junior associates and ensure their proper execution and successful completion.
  • Ensure the availability of all required resources for the execution of service requests.
  • Liaise with investigators regarding service requests.
  • Participate in the planning, execution, and troubleshooting of service requests.
  • Provide research and input on new technologies and assays for testing to possibly develop and implement new service offerings.
  • Execute or manage the execution of projects testing new technologies, assays, or kits.
  • Analyze, summarize, and present findings at monthly R&D meetings.
  • Assist with the implementation of new technologies, assays, or kits into new service offerings by writing and reviewing standard operating procedures, service guidelines, and staff training guides, and training junior associates.
  • Receive, store, and document samples.
  • Attend meetings and seminars/webinars as assigned.


Experience & Skills:

  • Two (2) years of experience are required.
  • Ability to take on new challenges while independently executing new or unusual and complex technical procedures and protocols.
  • Operate state-of-the art instruments, including Illumina and Pacific Biosciences sequencers, single cell instruments, automated liquid handlers, tissue dissociators, flow cytometers, cell sorters, ultrasonicators, and fragment analyzers.
  • Interact with professionalism with teammates, peers, researchers, investigators, and support staff of diverse backgrounds and educational levels.
  • Critical analysis, problem-solving, troubleshooting, multitasking, time management, following through tasks with details, working independently with minimal supervision.
  • Respond to rapidly changing priorities and exceptionally diverse demands through constant interruptions in a fast-paced laboratory environment.
  • Work cooperatively with other personnel as part of a team to accomplish daily and weekly goals.

Working Title: Biomedical Specialist – Bioinformatics & Functional Genomics Core
Department: BMS – Bioinfo & Func Genomics
Business Entity: Academic / Research
Job Category: Family & Function,Academic / Research,Family & Function,Academic / Research
Job Specialty: UNASSIGNED
Position Type: Full-time
Shift Length: 8 hour shift
Shift Type: Day
Base Pay:$34.25 – $53.09

Our compensation philosophy

We offer competitive total compensation that includes pay, benefits, and other recognition programs for our employees. The base pay range shown above takes into account the wide range of factors that are considered in making compensation decisions including knowledge/skills; relevant experience and training; education/certifications/licensure; and other business and organizational factors. This base pay range does not include our comprehensive benefits package and any incentive payments that may be applicable to this role

Diversity and Inclusion at Cedars-Sinai

We are caretakers and innovators committed to the pursuit of equitable healthcare. But health equity is not possible without representation. Our commitment to diversity goes beyond demographics or checking boxes. Our people must reflect the diverse identities, experiences and geographies of the communities and patients we serve – because that’s what our patients, colleagues and communities deserve. Quality Care and Research—For All, By All.

Cedars-Sinai is an Equal Employment Opportunity employer.

Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law. If you need a reasonable accommodation for any part of the employment process, please contact us by email at and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Cedars-Sinai will consider for employment qualified applicants with criminal histories, in accordance with the Los Angeles Fair Chance Initiative for Hiring.

At Cedars-Sinai, we are dedicated to the safety, health and wellbeing of our patients and employees. This includes protecting our patients from communicable diseases, such as influenza (flu) and COVID-19. For this reason, we require that all new employees receive a flu vaccine based on the seasonal availability of flu vaccine (typically during September through April each year) as a condition of employment, and annually thereafter as a condition of continued employment, subject to medical exemption or religious accommodation. For the same reason, you may also be required to receive other vaccines such as COVID-19 as a condition of employment. Cedars-Sinai reserves the right to make modifications to its required list of vaccines as required by law and/or policy.

Read more here: Source link