Normative Modeling of Brain Morphometry Across the Lifespan Using CentileBrain: Algorithm Benchmarking and Model Optimization,bioRxiv – Bioinformatics

Background Normative modeling is a statistical approach to quantify the degree to which a particular individual-level measure deviates from the pattern observed in a normative reference population. When applied to human brain morphometric measures it has the potential to inform about the significance of normative deviations for health and disease. Normative models can be implemented using a variety of algorithms that have not been systematically appraised.

中文翻译:








使用 CentileBrain 对整个生命周期的大脑形态学进行规范建模:算法基准测试和模型优化



背景规范建模是一种统计方法,用于量化特定个体水平测量偏离规范参考人群中观察到的模式的程度。当应用于人脑形态测量时,它有可能告知规范偏差对健康和疾病的重要性。可以使用尚未系统评估的各种算法来实施规范模型。






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