EC 1.3.99.39 Enzyme |
carotenoid phi-ring synthase;
crtU (gene name) (ambiguous)
Oxidoreductases;
Acting on the CH-CH group of donors;
With unknown physiological acceptors
carotenoid beta-ring:acceptor oxidoreductase/methyltranferase (phi-ring-forming)
The enzyme, found in green sulfur bacteria, some cyanobacteria and some actinobacteria, introduces additional double bonds to the carotenoid beta-end group, leading to aromatization of the ionone ring. As a result, one of the methyl groups at C-1 is transferred to position C-2. It is involved in the biosynthesis of carotenoids with phi-type aromatic end groups such as chlorobactene, beta-isorenieratene, and isorenieratene.
EC 1.3.99.39 created 2018
ec01110 | Biosynthesis of secondary metabolites |
K09879 | carotenoid phi-ring synthase / carotenoid chi-ring synthase |
SAMY: | DB32_005179 DB32_008580 |
MGRO: | FZ046_15700 FZ046_20810 |
MCOO: | MCOO_47810 MCOO_48880 |
MPHL: | MPHLCCUG_02043(pds_2) |
MTHN: | 4412656_00241(pds) |
MAUU: | NCTC10437_01603(pds_1) NCTC10437_04608(pds_2) |
MPSC: | MPSYJ_34700 MPSYJ_51550 |
MHEV: | MHEL_00200 MHEL_60530 |
MSAR: | MSAR_05720 MSAR_34970 |
MPOF: | MPOR_18260 MPOR_21090 |
MFLV: | NCTC10271_03420(pds_2) |
MRF: | MJO55_06575 MJO55_14810 |
RCR: | NCTC10994_03817(pds_2) |
SGR: | SGR_56t(crtU2) SGR_6826(crtU) SGR_7083t(crtU3) |
SGB: | WQO_01605 WQO_03645 |
SLE: | sle_65890(sle_65890) |
STRD: | NI25_03600 NI25_35260 |
SGF: | HEP81_07765 HEP81_07985 |
STUI: | GCM10017668_46170(crtU) |
SNIG: | HEK616_76690(crtU) |
APRE: | CNX65_19075 CNX65_24395 |
AMI: | Amir_3813 Amir_4947 |
SYY: | SYNGTS_1358(sll0254) |
SYT: | SYNGTI_1358(sll0254) |
SYS: | SYNPCCN_1357(sll0254) |
SYQ: | SYNPCCP_1357(sll0254) |
SYP: | SYNPCC7002_A1248(crtU) |
ARP: | NIES39_D01920(crtL) |
PAGH: | NIES204_24750(crtL) |
GML: | ISF26_00135 ISF26_16075 |
NSPH: | BDGGKGIB_03034(pds_2) |
PROC: | Ptc2401_01837(petC_1) |
Moshier SE, Chapman DJ
Biosynthetic studies on aromatic carotenoids. Biosynthesis of chlorobactene.
Krugel H, Krubasik P, Weber K, Saluz HP, Sandmann G.
Functional analysis of genes from Streptomyces griseus involved in the synthesis of isorenieratene, a carotenoid with aromatic end groups, revealed a novel type of carotenoid desaturase.
Frigaard NU, Maresca JA, Yunker CE, Jones AD, Bryant DA.
Genetic manipulation of carotenoid biosynthesis in the green sulfur bacterium Chlorobium tepidum.
ExPASy – ENZYME nomenclature database: | 1.3.99.39 |
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