BalanCD CHO Perfusion – Powder

BalanCD CHO Perfusion is a chemically defined medium that is optimized for the growth and production of suspension CHO cell cultures in continuous, steady-state, and N-1 perfusion cultures. As a high performing medium, it can achieve key perfusion metrics including cell-specific productivity, volumetric productivity, and cell-specific perfusion rate (CSPR).

BalanCD CHO Perfusion medium meets the requirements of large-scale industrial cell cultures and is intended for long-term, continuous culturing of CHO cells.

  • Optimize perfusion processes to achieve cost-effective production of biotherapeutics
  • Complete, ready-to-use medium that supports cell growth, cell expansion, and production of monoclonal antibodies and recombinant proteins
  • Scalable from small shake flasks to large-scale perfusion bioreactors
  • Supports a variety of CHO sub-types
  • Delivers consistent, optimal cell productivities at 1 vessel volume per day (VVD)

BalanCD CHO Perfusion is intended for further manufacturing use only.

Standard Packaging Size: 10 L bottle

Custom Packaging Sizes: Available upon request.

For more information on Drug Master FilesĀ click here.

Figure 1. Perfusion metrics including volumetric productivity (VP), cell-specific productivity (qP), and cell-specific perfusion rate (CSPR) were calculated at steady states SS1 (45 million cells/mL) and SS2 (70 million cells/mL) for BalanCD CHO Perfusion. Perfusion metrics at SS2 demonstrate that VP, qP and CSPR can be improved by pushing the culture to higher cell densities. VP and qP values increased 4x and 2.5x fold, respectively, while the CSPR value decreased by 24%, demonstrating high productivity and performance from BalanCD CHO Perfusion at higher cell densities.


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