Postdoctoral Fellow in Epigenetics at European Molecular Biology Laboratory (EMBL)

About the team/job

The Hackett group studies the epigenetic basis of genome regulation across scales, from chromatin function to organism response. We aim to to understand the causal and context-specific impact of chromatin states in healthy and diseased tissues, and the potential for epigenetic memory. More information can be found at www.embl.org/groups/hackett/

Your role

We seek an ERC-funded postdoctoral scientist to investigate the precise mechanistic function of chromatin modifications. The successful candidate will work on a cutting-edge experimental research project using high-throughput CRISPR genetics, epigenetic editing, multi-omics, and organoids. The objective is to uncover the regulatory logic by which distinct chromatin states interact with the genomic context and cellular identity, to shape gene expression patterns. You will enjoy substantial freedom (if desired) to follow curiosity-driven hypotheses, based on novel screening datasets.

You have

• PhD in Molecular or Chromatin Biology
• Skills in (epi)genomics techniques and/or Biochemistry methods
• Experience with mammalian tissue culture or stem cells
• Independence and ability to solve problems
• Excellent communication and interpersonal skills with the highest ethical standards.

You might also have

• Experience in high-throughput (CRISPR) screens
• Skills in Bioinformatics and (epi)genomics data analysis

Why join us

EMBL is an inclusive, equal opportunity employer offering a highly attractive salary and benefits appropriate to a premier international research organisation. We have an informal, curiosity-driven culture, and extensive training and professional development opportunities. The environment is supportive, collegial and family-friendly to foster development of ambitious research.

The EMBL Rome campus is a highly interactive international institute, with a focus on Epigenetics and Neurobiology. Research on site is supported by world-class core facilities, including advanced microscopy, FACS, genomics, mouse transgenics, viral production and bioinformatics. The campus is situated just outside Rome, and enables nearby access to the coast, the Apennine mountains, and immersion in the lifestyle and culture of historic Rome.

What else you need to know

The initial contract is for a period of three years, with the potential to extend up to five years. We actively encourage applications from all genders, cultures, ethnic groups and all demographics.

The working language is English.

Please submit your application online including your CV with references, and a cover letter detailing your motivation, background, and future research interests.

For more information on the project and lab life at EMBL Rome, please contact Jamie Hackett at: jamie.hackett@embl.it


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