Using t test to compare z-scores from RNA expression data

Using t test to compare z-scores from RNA expression data

2

Hi! I need to compare the expression of ~220 genes between two groups (n = 62 and n = 777). I have a dataframe with Z-scores for the expression of those genes (they were actually part of the same group, but I split them based on some criteria, but the z-scores were calculated using them as a group). I have no access to other kind of data like count data. Is it right to use a t-test or a moderated t test to compare them? would be better to use a wilcox test?

Thanks in advance


expression


Statistics


Z-Score


RNA

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