PRSice-2 using SNPs with extremely low P-value

PRSice-2 using SNPs with extremely low P-value

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I would like to construct a Polygenic risk score using PRSice-2. However, our summary statistics contains a very small P-value, such as P-value=5.0×10^-1200.
Perhaps that is why we cannot use this summary statistics to construct the PRS. How can I solve this problem? I would be grateful if you could enlighten me.


PRSice-2


SNP

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