DE genes across multiple scRNAseq clusters-are they significantly enriched?

DE genes across multiple scRNAseq clusters-are they significantly enriched?

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I have a dataset comparing 2 samples. My experimental sample has thousands of differential expressed genes in each cell clusters. I am interested in looking at the genes that appear in multiple clusters to get a sense for genes and pathways that are globally altered in my sample. Is there a good test to see if a gene is appearing in multiple clusters by chance or if it a significant enrichment?


Single-cell

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